# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1248716 | F | Antiviral activity against HIV1 3B infected in human CEM-SS cells assessed as inhibition of viral replication after 6 days by XTT assay | Human immunodeficiency virus 1 | 47 | organism-based format | Scientific Literature | ||
2. | ALA1248717 | A | Cytotoxicity against human CEM-SS cells infected with HIV1 3B after 6 days by XTT assay | Homo sapiens | 47 | cell-based format | Scientific Literature | ||
3. | ALA1248718 | A | Therapeutic index, ratio of TC50 for human CEM-SS cells infected with HIV1 3B to EC50 for HIV1 3B infected in human CEM-SS cells | 28 | cell-based format | Scientific Literature | |||
4. | ALA4822499 | P | Helicity of the compound in TFE aqueous solution by CD spectroscopy | 5 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA4822500 | A | Stability of the compound assessed as trypsin (unknown origin)-mediated degradation using pH 7.4 PBS buffer measured for 60 mins by HPLC analysis | Homo sapiens | 1 | protein format | Scientific Literature | ||
6. | ALA4822501 | A | Stability of the compound assessed as trypsin (unknown origin)-mediated degradation by measuring half life using pH 7.4 PBS buffer by HPLC analysis | Homo sapiens | 2 | protein format | Scientific Literature | ||
7. | ALA4822502 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 96 hrs b y CCK-8 assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA4822503 | F | Cytotoxicity against human LNCaP C4-2B cells assessed as reduction in cell viability measured after 96 hrs b y CCK-8 assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
9. | ALA4822504 | A | Cytotoxicity against human HEK293T cells assessed as reduction in cell viability measured after 96 hrs b y CCK-8 assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
10. | ALA4822507 | A | Hemolytic activity in rabbit red blood cells assessed as hemoglobin release | Oryctolagus cuniculus | 5 | cell-based format | Scientific Literature | ||
11. | ALA5156681 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as inhibition of bacterial growth incubated for 16 hrs by broth microdilution method | Staphylococcus aureus | 20 | organism-based format | Scientific Literature | ||
12. | ALA5156682 | F | Antibacterial activity against Staphylococcus aureus BNCC 186335 assessed as inhibition of bacterial growth incubated for 16 hrs by broth microdilution method | Staphylococcus aureus | 20 | organism-based format | Scientific Literature | ||
13. | ALA5156683 | F | Antibacterial activity against Listeria monocytogenes assessed as inhibition of bacterial growth incubated for 16 hrs by broth microdilution method | Listeria monocytogenes | 20 | organism-based format | Scientific Literature | ||
14. | ALA5156685 | F | Antibacterial activity against Pseudomonas aeruginosa BNCC 125486 assessed as inhibition of bacterial growth incubated for 16 hrs by broth microdilution method | Pseudomonas aeruginosa | 20 | organism-based format | Scientific Literature | ||
15. | ALA5156686 | F | Antibacterial activity against Escherichia coli BNCC 133264 assessed as inhibition of bacterial growth incubated for 16 hrs by broth microdilution method | Escherichia coli | 20 | organism-based format | Scientific Literature | ||
16. | ALA5156687 | F | Antibacterial activity against cephalosporin-resistant Escherichia coli BNCC 133264 assessed as inhibition of bacterial growth incubated for 16 hrs by broth microdilution method | Escherichia coli | 20 | organism-based format | Scientific Literature | ||
17. | ALA5156688 | T | Hemolytic activity against human RBC assessed as concentration required to cause 10% hemolysis | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
18. | ALA5156689 | T | Cytotoxicity against human HEK293T cells assessed as cell survival rate at 8 to 128 Ug/ml incubated for 24 hrs by MTT assay relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature |