# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1243425 | F | Enhancement of autophagy in rat PC12 cells assessed as decrease in alpha-synuclein A53T mutant level at 43 uM by immunoblotting | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
2. | ALA1243426 | A | Cytotoxicity against african green monkey COS7 cells at 47 uM after 24 hrs by FACS analysis | Chlorocebus aethiops | 2 | cell-based format | Scientific Literature | ||
3. | ALA1243428 | B | Inhibition of EGFP-tagged huntingtin aggregation expressed in african green monkey COS7 cells at 47 uM after 48 hrs by Western blot analysis | 2 | cell-based format | Scientific Literature | |||
4. | ALA1243430 | B | Inhibition of EGFP-tagged huntingtin expressed in african green monkey COS7 cells assessed as protection against protein-induced cell death at 47 uM after 48 hrs by Western blot analysis | 2 | cell-based format | Scientific Literature | |||
5. | ALA1243432 | B | Inhibition of EGFP-tagged huntingtin aggregation in MEF harboring Atg5 gene at 47 uM after 48 hrs by Western blot analysis | Mus musculus | 3 | single protein format | Scientific Literature | ||
6. | ALA1243434 | B | Inhibition of EGFP-tagged huntingtin aggregation in Atg5-deficient MEF at 47 uM after 48 hrs by Western blot analysis | Mus musculus | 3 | single protein format | Scientific Literature | ||
7. | ALA1243436 | F | Induction of autophagy in human HeLa cells harboring MAP1LC3 gene at 47 uM after 24 hrs by DAPI staining-based fluorescence microscopy | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA1243438 | F | Increase in MAP1LC3 level in bafilomycin A1-treated human HeLa cells at 47 uM treated fro 24 hrs before bafilomycin A1 challenge by immunoblotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA1243440 | F | Neuroprotective activity in Drosophila melanogaster Huntington's disease model harboring huntington protein mutant assessed as protection against neurodegeneration at 100 uM | Drosophila melanogaster | 2 | organism-based format | Scientific Literature | ||
10. | ALA1243442 | A | Toxicity against Drosophila melanogaster Huntington's disease model at 100 uM | Drosophila melanogaster | 2 | organism-based format | Scientific Literature | ||
11. | ALA1243444 | B | Inhibition of mTOR phosphorylation expressed in african green monkey COS7 cells at 47 uM by Western blot analysis | 2 | cell-based format | Scientific Literature | |||
12. | ALA1243446 | F | Effect on ATg6 level in african green monkey COS7 cells at 47 uM after 24 hrs by immunoblotting | Chlorocebus aethiops | 2 | cell-based format | Scientific Literature | ||
13. | ALA1243447 | F | Effect on ATg5 level in african green monkey COS7 cells at 47 uM after 24 hrs by immunoblotting | Chlorocebus aethiops | 2 | cell-based format | Scientific Literature | ||
14. | ALA1243448 | F | Effect on ATg7 level in african green monkey COS7 cells at 47 uM after 24 hrs by immunoblotting | Chlorocebus aethiops | 2 | cell-based format | Scientific Literature | ||
15. | ALA1243449 | F | Effect on ATg12 level in african green monkey COS7 cells at 47 uM after 24 hrs by immunoblotting | Chlorocebus aethiops | 2 | cell-based format | Scientific Literature | ||
16. | ALA1243450 | F | Increase in conjugated Atg12-Atg5 level in african green monkey COS7 cells at 47 uM after 24 hrs by immunoblotting | Chlorocebus aethiops | 2 | cell-based format | Scientific Literature | ||
17. | ALA1243456 | B | Inhibition of proteasome activity in human HeLa cells assessed as induction of ubiquitinG76V-EGFP reporter level at 47 uM after 24 hrs by immunoblotting | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
18. | ALA1243458 | F | Enhancement of rapamycin-induced clearance of alpha-synuclein A53T mutant protein in rat PC12 cells at 140 uM after 8 hrs by immunoblotting | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
19. | ALA1243459 | F | Enhancement of rapamycin-induced clearance of alpha-synuclein A53T mutant protein in rat PC12 cells at 43 uM after 8 hrs by immunoblotting | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
20. | ALA1243461 | B | Inhibition of EGFP-tagged huntingtin aggregation expressed in african green monkey COS7 cells at 140 uM after 24 hrs by Western blot analysis in presence of 0.2 uM rapamycin | 1 | cell-based format | Scientific Literature |