# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1250027 | B | Inhibition of recombinant human CD40L:mouse CD8 tail binding to human CD40 by surface plasmon resonance method | Homo sapiens | 6 | ALA1240299 | single protein format | Scientific Literature | |
2. | ALA1250028 | B | Binding affinity to human Tumor necrosis factor receptor 2 by surface plasmon resonance method | Homo sapiens | 1 | ALA1240299 | single protein format | Scientific Literature | |
3. | ALA1250029 | B | Binding affinity to human TNF-related apoptosis-inducing ligand receptor 1 by surface plasmon resonance method | Homo sapiens | 1 | ALA1240299 | single protein format | Scientific Literature | |
4. | ALA1250030 | B | Binding affinity to human lymphotoxin beta receptor by surface plasmon resonance method | Homo sapiens | 1 | ALA1240299 | single protein format | Scientific Literature | |
5. | ALA1250031 | B | Binding affinity to mouse B-cell maturation protein by surface plasmon resonance method | Mus musculus | 1 | ALA1240299 | single protein format | Scientific Literature | |
6. | ALA1250032 | B | Binding affinity to human Ectodysplasin-A receptor by surface plasmon resonance method | Homo sapiens | 1 | ALA1240299 | single protein format | Scientific Literature | |
7. | ALA1250033 | F | Induction of apoptosis in CD40-positive human BL41 cells assessed as decrease in mitochondrial membrane potential after 16 hrs by mean fluorescence intensity | Homo sapiens | 6 | ALA1240299 | cell-based format | Scientific Literature | |
8. | ALA1250034 | F | Induction of apoptosis in CD40-positive human BL41 cells assessed as decrease in reduction in DiOC6 dye uptake after DAPI staining by epifluorescence microscopy | Homo sapiens | 6 | ALA1240299 | cell-based format | Scientific Literature | |
9. | ALA1250035 | F | Induction of apoptosis in CD40-positive human BL41 cells assessed as level of CD40 expression by mean fluorescence intensity | Homo sapiens | 6 | ALA1240299 | cell-based format | Scientific Literature | |
10. | ALA1250036 | F | Induction of apoptosis in CD40-positive human BL41 cells assessed as detection of phosphatidylserine expression using annexin V-FITC and propidium iodine staining by flow cytometry | Homo sapiens | 6 | ALA1240299 | cell-based format | Scientific Literature | |
11. | ALA1250078 | F | Induction of apoptosis in mouse CD40-expressing mouse A20 cells assessed as decrease in mitochondrial membrane potential after 16 hrs by mean fluorescence intensity | Mus musculus | 1 | ALA1240299 | cell-based format | Scientific Literature | |
12. | ALA1250079 | F | Induction of mouse D1 cell maturation assessed as CD80 expression at 5 to 10 uM after 48 hrs by flow cytometry in presence of 10 ug/ml LPS inhibitor polymyxin B | Mus musculus | 4 | ALA1240299 | cell-based format | Scientific Literature | |
13. | ALA1250080 | F | Induction of mouse D1 cell maturation assessed as CD86 expression at 5 to 10 uM after 48 hrs by flow cytometry in presence of 10 ug/ml LPS inhibitor polymyxin B | Mus musculus | 4 | ALA1240299 | cell-based format | Scientific Literature | |
14. | ALA1250081 | F | Induction of mouse D1 cell maturation assessed as CD54 expression at 5 to 10 uM after 48 hrs by flow cytometry in presence of 10 ug/ml LPS inhibitor polymyxin B | Mus musculus | 4 | ALA1240299 | cell-based format | Scientific Literature | |
15. | ALA1250082 | F | Activation of NF-kappaB pathway in mouse D1 cells assessed as increased degradation of IkappaBalpha protein by immunoblotting assay | Mus musculus | 1 | ALA1240299 | cell-based format | Scientific Literature | |
16. | ALA1250083 | F | Induction of interleukin-12 production in mouse D1 cells by RT-PCR method | Mus musculus | 1 | ALA1240299 | cell-based format | Scientific Literature | |
17. | ALA1250086 | B | Binding affinity to human TNFR1 by surface plasmon resonance method | Homo sapiens | 1 | ALA1240299 | single protein format | Scientific Literature |