| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1917982 | B | Inhibition of soybean 15-LOX type 1-B assessed as inhibition of conversion of linoleic acid to (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate preincubated for 10 mins before substrate addition measured after 6 mins by spectrophotometry | Glycine max | 2 | assay format | Scientific Literature | ||
| 2. | ALA1917983 | B | Inhibition of human 5-LOX in human peripheral blood mononuclear leukocytes assessed as inhibition of calymycin A23187-stimulated LTB4 production preincubated for 15 mins before stimulation measured after 15 mins by enzyme immunoassay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 3. | ALA1917984 | B | Inhibition of 5-LOX in calcium ionophore A23187-stimulated NMRI mouse macrophage assessed as inhibition of LTC4 production preincubated for 60 mins before stimulation measured after 2 hrs by ELISA | Mus musculus | 2 | single protein format | Scientific Literature | ||
| 4. | ALA1917985 | A | Cytotoxicity against NMRI mouse macrophages by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1917986 | F | Antioxidant activity assessed as DPPH radical scavenging activity | 2 | assay format | Scientific Literature | |||
| 6. | ALA1918161 | F | Metal chelating activity of the compound assessed as formation of iron complex in PBS at pH 7.4 at 50 uM after 10 secs by UV-vis spectrometry in presence of 100 uM FeSO4 | 1 | assay format | Scientific Literature | |||
| 7. | ALA1918162 | F | Metal chelating activity of the compound assessed as formation of copper complex in PBS at pH 7.4 at 50 uM after 10 secs by UV-vis spectrometry in presence of 100 uM CuSO4 | 1 | assay format | Scientific Literature | |||
| 8. | ALA1918163 | F | Metal chelating activity of the compound assessed as formation of iron complex in PBS at pH 7.4 at 50 uM after 10 secs by UV-vis spectrometry in presence of 100 uM FeCl3 | 1 | assay format | Scientific Literature | |||
| 9. | ALA1918164 | B | Inhibition of COX1 in human platelets assessed as inhibition of conversion of arachidonic acid to PGE2 preincubated for 15 mins before substrate addition measured after 15 mins by enzyme immunoassay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA1918165 | B | Inhibition of human recombinant COX2 expressed in insect Sf21 cells assessed as inhibition of conversion of arachidonic acid to PGE2 preincubated for 15 mins before substrate addition measured after 5 mins by enzyme immunoassay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA1918166 | B | Inhibition of human 5-LOX in human peripheral blood mononuclear leukocytes assessed as inhibition of calymycin A23187 stimulated LTB4 production at 1 uM preincubated for 15 mins before stimulation measured after 15 mins by enzyme immunoassay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA1918167 | B | Inhibition of human recombinant COX2 expressed in insect Sf21 cells assessed as inhibition of conversion of arachidonic acid to PGE2 at 1 uM preincubated for 15 mins before substrate addition measured after 5 mins by enzyme immunoassay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA1918168 | B | Inhibition of COX1 in human platelets assessed as inhibition of conversion of arachidonic acid to PGE2 at 10 uM preincubated for 15 mins before substrate addition measured after 15 mins by enzyme immunoassay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA1918169 | B | Inhibition of human 5-LOX in human peripheral blood mononuclear leukocytes assessed as inhibition of calymycin A23187 stimulated LTB4 production at 10 uM preincubated for 15 mins before stimulation measured after 15 mins by enzyme immunoassay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA1918170 | B | Inhibition of human 5-LOX in human peripheral blood mononuclear leukocytes assessed as inhibition of calymycin A23187 stimulated LTB4 production at 0.1 uM preincubated for 15 mins before stimulation measured after 15 mins by enzyme immunoassay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA1918171 | B | Inhibition of human 5-LOX in human peripheral blood mononuclear leukocytes assessed as inhibition of calymycin A23187 stimulated LTB4 production at 10 nM preincubated for 15 mins before stimulation measured after 15 mins by enzyme immunoassay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA1918172 | B | Inhibition of human recombinant COX2 expressed in insect Sf21 cells assessed as inhibition of conversion of arachidonic acid to PGE2 at 10 uM preincubated for 15 mins before substrate addition measured after 5 mins by enzyme immunoassay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA1918173 | B | Inhibition of human recombinant COX2 expressed in insect Sf21 cells assessed as inhibition of conversion of arachidonic acid to PGE2 at 0.1 uM preincubated for 15 mins before substrate addition measured after 5 mins by enzyme immunoassay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA1918174 | B | Inhibition of human recombinant COX2 expressed in insect Sf21 cells assessed as inhibition of conversion of arachidonic acid to PGE2 at 10 nM preincubated for 15 mins before substrate addition measured after 5 mins by enzyme immunoassay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA1918175 | B | Inhibition of COX1 in human platelets assessed as inhibition of conversion of arachidonic acid to PGE2 at 1 uM preincubated for 15 mins before substrate addition measured after 15 mins by enzyme immunoassay | Homo sapiens | 1 | assay format | Scientific Literature |
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