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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA1247184 B Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scintillation counting Homo sapiens 8 ALA1240498 cell-based format Scientific Literature 2. ALA1247185 B Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scintillation counting Homo sapiens 2 ALA1240498 cell-based format Scientific Literature 3. ALA1247186 B Inhibition of GLUT1-mediated [3H]2-deoxy-glucose uptake in rat L6 cells after 15 mins by liquid scintillation counting Rattus norvegicus 2 ALA1240498 cell-based format Scientific Literature 4. ALA1247187 F Antihyperglycemic activity in Sprague-Dawley rat assessed as induction of urinary glucose excretion per 200 gram of body weight at 30 mg/kg, po after 24 hrs Rattus norvegicus 8 ALA1240498 organism-based format Scientific Literature 5. ALA1247188 A Cmax in Sprague-Dawley rat at 10 mg/kg, po Rattus norvegicus 2 ALA1240498 organism-based format Scientific Literature 6. ALA1247189 A Tmax in Sprague-Dawley rat at 10 mg/kg, po Rattus norvegicus 2 ALA1240498 organism-based format Scientific Literature 7. ALA1247191 A AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, po Rattus norvegicus 2 ALA1240498 organism-based format Scientific Literature 8. ALA1247335 A AUC (0 to infinity) in Sprague-Dawley rat at 3 mg/kg, iv Rattus norvegicus 1 ALA1240498 organism-based format Scientific Literature 9. ALA1247337 A Half life in Sprague-Dawley rat at 10 mg/kg, po Rattus norvegicus 2 ALA1240498 organism-based format Scientific Literature 10. ALA1247338 A Half life in Sprague-Dawley rat at 3 mg/kg, iv Rattus norvegicus 1 ALA1240498 organism-based format Scientific Literature 11. ALA1247340 A Total clearance in Sprague-Dawley rat at 3 mg/kg, iv Rattus norvegicus 1 ALA1240498 organism-based format Scientific Literature 12. ALA1247342 A Volume of distribution at steady state in Sprague-Dawley rat at 3 mg/kg, iv Rattus norvegicus 1 ALA1240498 organism-based format Scientific Literature 13. ALA1247343 A Oral bioavailability in Sprague-Dawley rat at 10 mg/kg Rattus norvegicus 2 ALA1240498 organism-based format Scientific Literature 14. ALA1247344 F Antihyperglycemic activity in high fat diet KK/Ta Jcl mouse assessed as reduction of blood glucose level at 3 mg/kg, po after 6 hrs relative to control Mus musculus 1 ALA1240498 organism-based format Scientific Literature 15. ALA1247345 F Antihyperglycemic activity in normoglycemic C57BL/6N mouse assessed as reduction of blood glucose level at 3 mg/kg, po after 6 hrs Mus musculus 1 ALA1240498 organism-based format Scientific Literature 16. ALA1247346 T Toxicity in high fat diet KK/Ta Jcl mouse assessed as reduction of food intake at 3 mg/kg, po Mus musculus 1 ALA1240498 organism-based format Scientific Literature