# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1250983 | B | Blockade of mouse HCN1 expressed in HEK293 cells at 5 uM at -120 f-current amplitude by patch-clamp electrophysiological assay relative to control | Mus musculus | 12 | cell-based format | Scientific Literature | ||
2. | ALA1250984 | B | Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assay | Mus musculus | 9 | cell-based format | Scientific Literature | ||
3. | ALA1250985 | B | Blockade of human HCN4 expressed in HEK293 cells at 5 uM at -120 f-current amplitude by patch-clamp electrophysiological assay relative to control | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
4. | ALA1250986 | B | Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assay | Mus musculus | 9 | cell-based format | Scientific Literature | ||
5. | ALA1250987 | B | Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
6. | ALA1250988 | B | Blockade of HCN in guinea pig spontaneously beating atria assessed as reduction of heart rate measured for 15 mins | Cavia porcellus | 9 | tissue-based format | Scientific Literature | ||
7. | ALA1250989 | B | Selectivity ratio of EC50 for mouse HCN2 to EC50 for mouse HCN1 | Mus musculus | 1 | assay format | Scientific Literature | ||
8. | ALA1250990 | B | Selectivity ratio of EC50 for mouse HCN2 to EC50 for human HCN4 | 1 | assay format | Scientific Literature |