# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3822265 | Binding | Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assay | Equus caballus | 7 | ALA3817788 | single protein format | Scientific Literature | |
2. | ALA3822266 | Binding | Selectivity index, ratio of IC50 for equine serum BChE to IC50 for AChE (unknown origin) | 7 | ALA3817788 | assay format | Scientific Literature | ||
3. | ALA3822267 | Binding | Selectivity index, ratio of IC50 for AChE (unknown origin) to IC50 for equine serum BChE | 7 | ALA3817788 | assay format | Scientific Literature | ||
4. | ALA3822138 | Binding | Inhibition of AChE (unknown origin) at 100 ug/ml using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assay | Homo sapiens | 7 | ALA3817788 | single protein format | Scientific Literature | |
5. | ALA3822139 | Binding | Inhibition of equine serum BChE at 100 ug/ml using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assay | Equus caballus | 7 | ALA3817788 | single protein format | Scientific Literature | |
6. | ALA3822141 | Binding | Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assay | Homo sapiens | 7 | ALA3817788 | single protein format | Scientific Literature | |
7. | ALA1251279 | Binding | Induction of Escherichia coli pBR322 DNA cleavage assessed as open circular form of DNA at 25 uM after 45 mins by agarose gel electrophoresis in presence of copper | Escherichia coli | 4 | ALA1250531 | nucleic acid format | Scientific Literature | |
8. | ALA1251280 | Binding | Induction of Escherichia coli pBR322 DNA cleavage at 25 uM after 45 mins under anoxic condition by agarose gel electrophoresis in presence of copper | Escherichia coli | 2 | ALA1250531 | nucleic acid format | Scientific Literature | |
9. | ALA1251281 | Binding | Induction of Escherichia coli pBR322 DNA cleavage assessed as linear form of DNA at 25 uM after 45 mins by agarose gel electrophoresis in presence of copper | Escherichia coli | 3 | ALA1250531 | nucleic acid format | Scientific Literature | |
10. | ALA1251358 | Functional | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay | Homo sapiens | 5 | ALA1250531 | cell-based format | Scientific Literature | |
11. | ALA1251359 | Functional | Cytotoxicity against human MCF7 cells at 50 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA1250531 | cell-based format | Scientific Literature | |
12. | ALA2209268 | Functional | Antimycobacterial activity against Mycobacterium tuberculosis H37Ra | Mycobacterium tuberculosis | 57 | ALA2203104 | organism-based format | Scientific Literature | |
13. | ALA4123805 | Binding | Inhibition of porcine pancreatic alpha-amylase using starch as substrate after 30 mins by iodine reagent based assay | Sus scrofa | 8 | ALA4118204 | single protein format | Scientific Literature | |
14. | ALA4123806 | Binding | Inhibition of rat intestinal alpha-glucosidase using p-nitrophenyl alpha-D-glucopyranoside as substrate pretreated for 10 mins followed by substrate addition measured after 5 mins | Rattus norvegicus | 8 | ALA4118204 | assay format | Scientific Literature | |
15. | ALA4123807 | ADME | Cytotoxicity against rat L6 cells up to 50 uM after 24 hrs by MTT assay | Rattus norvegicus | 7 | ALA4118204 | cell-based format | Scientific Literature | |
16. | ALA4123808 | Binding | Antiglycation activity in bovine serum albumin assessed as inhibition of advanced glycated end product formation after 24 hrs in presence of alpha-D-glucose by fluorescence assay | Bos taurus | 8 | ALA4118204 | single protein format | Scientific Literature | |
17. | ALA4123810 | Functional | Antidiabetic activity in rat L6 cells assessed as effect on 2-NBDG uptake at 10 uM pretreated for 24 hrs followed by 2-NBDG addition after 30 mins by FACS (Rvb = 20%) | Rattus norvegicus | 7 | ALA4118204 | cell-based format | Scientific Literature | |
18. | ALA4123811 | Functional | Antidiabetic activity in rat L6 cells assessed as effect on 2-NBDG uptake at 25 uM pretreated for 24 hrs followed by 2-NBDG addition after 30 mins by FACS (Rvb = 20%) | Rattus norvegicus | 7 | ALA4118204 | cell-based format | Scientific Literature | |
19. | ALA4123812 | Functional | Antidiabetic activity in rat L6 cells assessed as effect on 2-NBDG uptake at 50 uM pretreated for 24 hrs followed by 2-NBDG addition after 30 mins by FACS (Rvb = 20%) | Rattus norvegicus | 7 | ALA4118204 | cell-based format | Scientific Literature | |
20. | ALA4123813 | Functional | Antidiabetic activity in rat L6 cells assessed as increase in 2-NBDG uptake pretreated for 24 hrs followed by 2-NBDG addition after 30 mins by FACS | Rattus norvegicus | 7 | ALA4118204 | cell-based format | Scientific Literature |