| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1250752 | F | Antiproliferative activity against human H441 cells assessed as decrease of hexosaminidase activity after 24 hrs | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 2. | ALA4147132 | B | Inhibition of IKKbeta in human MGC-803 cells assessed as TNF-alpha induced I-kappa-B-alpha degradation at 1 to 10 uM preincubated for 1 hr followed by TNF-alpha stimulation and measured after 10 mins by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4147133 | B | Inhibition of IKKbeta (unknown origin) using FAM-P22 as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by mobility shift assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 4. | ALA4147134 | B | Inhibition of TNF-alpha induced IKKalpha/beta phosphorylation in human SGC-7901 cells preincubated for 1 hr followed by TNF-alpha stimulation and measured after 10 mins by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4147135 | B | Inhibition of TNF-alpha induced IKKalpha/beta phosphorylation in human MGC-803 cells preincubated for 1 hr followed by TNF-alpha stimulation and measured after 10 mins by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4147136 | B | Inhibition of IKKbeta in human SGC-7901 cells assessed as TNF-alpha induced I-kappa-B-alpha degradation at 1 to 10 uM preincubated for 1 hr followed by TNF-alpha stimulation and measured after 10 mins by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4147137 | B | Inhibition of IKKbeta in human SGC-7901 cells assessed as decrease in TNF-alpha induced p65 nuclear translocation at 10 uM preincubated for 1 hr followed by TNF-alpha stimulation and measured after 1 hr by DAPI staining-based fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4147138 | F | Antiproliferative activity against human HeLa 229 cells after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4147139 | F | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4147140 | F | Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4147141 | F | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4147142 | F | Cell cycle arrest in human SGC7901 cells assessed as accumulation of cells at G2/M phase at 1 to 10 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4147143 | F | Cell cycle arrest in human SGC7901 cells assessed as decrease in cyclinB1 levels at 1 to 10 uM after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4147144 | F | Cell cycle arrest in human SGC7901 cells assessed as decrease in Cdc2 p34 levels after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4147145 | F | Cell cycle arrest in human MGC803 cells assessed as accumulation of cells at G2/M phase at 1 to 10 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4147146 | F | Cell cycle arrest in human MGC803 cells assessed as decrease in cyclinB1 levels at 1 to 10 uM after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4147147 | F | Cell cycle arrest in human MGC803 cells assessed as decrease in Cdc2 p34 levels after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4147148 | F | Induction of apoptosis in human SGC7901 cells at 1 uM after 12 hrs by Annexin V-FITC staining-based FACS analysis (Rvb = 1.56%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4147149 | F | Induction of apoptosis in human SGC7901 cells at 5 uM after 12 hrs by Annexin V-FITC staining-based FACS analysis (Rvb = 1.56%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4147150 | F | Induction of apoptosis in human SGC7901 cells at 10 uM after 12 hrs by Annexin V-FITC staining-based FACS analysis (Rvb = 1.56%) | Homo sapiens | 2 | cell-based format | Scientific Literature |
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