| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1252531 | B | Displacement of [3H]Lys0-des-Arg9-BK at human bradykinin B1 receptor expressed in HEK293 cells | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 2. | ALA1252538 | B | Binding affinity to mouse bradykinin B1 receptor | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2092264 | B | Displacement of [3H]des-Arg10-KD from human recombinant B1 receptor expressed in HEK293 cells by liquid scintillation counter | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 4. | ALA2092266 | F | Antagonist activity at B1 receptor in human umbilical vein after 30 mins by Schild plot method | Homo sapiens | 34 | tissue-based format | Scientific Literature | ||
| 5. | ALA2092267 | F | Antagonist activity at B1 receptor in mouse fundus after 30 mins by Schild plot method | Mus musculus | 16 | assay format | Scientific Literature | ||
| 6. | ALA2092268 | F | Antagonist activity at rabbit B1 receptor by Schild plot method | Oryctolagus cuniculus | 1 | assay format | Scientific Literature | ||
| 7. | ALA2092269 | F | Antagonist activity at rat B1 receptor by Schild plot method | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 8. | ALA2092270 | A | Metabolic stability in human hepatic microsomes assessed as compound remaining at 1 uM after 30 mins | Homo sapiens | 33 | microsome format | Scientific Literature | ||
| 9. | ALA2092273 | A | Permeability across in human Caco2 cells at 50 uM | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 10. | ALA2092274 | A | Oral bioavailability in Swiss mouse at 5 mg/kg | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 11. | ALA2092275 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 12. | ALA2092277 | A | Half life in Swiss mouse at 5 mg/kg, po and 1 mg/kg, iv | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 13. | ALA2092278 | A | Half life in Sprague-Dawley rat at 10 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 14. | ALA2092280 | A | Clearance in Swiss mouse at 5 mg/kg, po and 1 mg/kg, iv | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 15. | ALA2092281 | A | Clearance in Sprague-Dawley rat at 10 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 16. | ALA2092283 | A | Volume of distribution in Swiss mouse at 5 mg/kg, po and 1 mg/kg, iv | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 17. | ALA2092284 | A | Volume of distribution in Sprague-Dawley rat at 10 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 18. | ALA2091465 | F | Antihyperalgesic activity in rat assessed as reversal of carrageenan-induced thermal hyperalgesia at 3 mg/kg, sc | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA2091466 | F | Antihyperalgesic activity in rat assessed as reversal of complete Freund's adjuvant-induced inflammatory pain at 10 mg/kg, sc | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA2091467 | F | Antinociceptive activity against rat assessed as formalin induced paw flinches at 10 mg/kg, sc administered 60 mins before formalin challenged measured up to 10 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
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