| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1260859 | A | Cytotoxicity against HEK293 cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 2. | ALA1260860 | F | Antimalarial activity against Plasmodium falciparum 3D7 infected in human erythrocyte | Plasmodium falciparum | 12 | organism-based format | Scientific Literature | ||
| 3. | ALA1260867 | F | Antimalarial activity against Plasmodium falciparum Dd2 infected in human erythrocyte | Plasmodium falciparum | 11 | organism-based format | Scientific Literature | ||
| 4. | ALA4481274 | P | Kinetic solubility of the compound in phosphate buffer at pH 6.5 after 30 mins by nephelometry | 11 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA4481275 | P | Kinetic solubility of the compound in HCL buffer at pH 2 after 30 mins by nephelometry | 11 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA4481276 | F | Antimalarial activity against artemisinin-resistant Plasmodium falciparum MRA1240 pretreated for 24 hrs followed by [3H]-hypoxanthine addition and measured after 24 hrs by [3H]-hypoxanthine growth inhibition assay | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA4481279 | A | Degradation half life in human liver microsomes at 0.5 uM in presence of NADPH generating system by LC-MS/MS analysis | Homo sapiens | 12 | microsome format | Scientific Literature | ||
| 8. | ALA4481280 | A | Degradation half life in mouse liver microsomes at 0.5 uM in presence of NADPH generating system by LC-MS/MS analysis | Mus musculus | 10 | microsome format | Scientific Literature | ||
| 9. | ALA4481281 | A | Intrinsic clearance in human liver microsomes at 0.5 uM up to 60 mins in presence of NADPH generating system by LC-MS/MS analysis | Homo sapiens | 12 | microsome format | Scientific Literature | ||
| 10. | ALA4481282 | A | Intrinsic clearance in mouse liver microsomes at 0.5 uM up to 60 mins in presence of NADPH generating system by LC-MS/MS analysis | Mus musculus | 10 | microsome format | Scientific Literature | ||
| 11. | ALA4481283 | F | Antimalarial activity against Plasmodium falciparum D6 pretreated for 24 hrs followed by [3H]-hypoxanthine addition and measured after 24 hrs by [3H]-hypoxanthine growth inhibition assay | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA4481284 | F | Antimalarial activity against Plasmodium falciparum W2 pretreated for 24 hrs followed by [3H]-hypoxanthine addition and measured after 24 hrs by [3H]-hypoxanthine growth inhibition assay | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA4481285 | F | Antimalarial activity against artemisinin-sensitive Plasmodium falciparum MRA1239 pretreated for 24 hrs followed by [3H]-hypoxanthine addition and measured after 24 hrs by [3H]-hypoxanthine growth inhibition assay | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA4481286 | F | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum FC27 infected in human RBC assessed as reduction in parasite growth after 35 to 56 hrs by nucleic acid staining based flow cytometry | Plasmodium falciparum | 5 | organism-based format | Scientific Literature | ||
| 15. | ALA4481287 | F | Antimalarial activity against chloroquine-resistant Plasmodium falciparum K1 infected in human RBC assessed as reduction in parasite growth after 35 to 56 hrs by nucleic acid staining based flow cytometry | Plasmodium falciparum | 5 | organism-based format | Scientific Literature | ||
| 16. | ALA4481288 | F | Antimalarial activity against multidrug-resistant Plasmodium falciparum clinical isolates infected assessed as reduction in parasite growth after 35 to 56 hrs by nucleic acid staining based flow cytometry | Plasmodium falciparum | 5 | organism-based format | Scientific Literature | ||
| 17. | ALA4481289 | F | Antimalarial activity against multidrug-resistant Plasmodium vivax clinical isolates assessed as reduction in parasite growth after 35 to 56 hrs by nucleic acid staining based flow cytometry | Plasmodium vivax | 5 | organism-based format | Scientific Literature | ||
| 18. | ALA4481290 | A | Plasma concentration in Swiss mouse at 2.8 mg/kg, iv via bolus administration measured up to 30 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4481291 | A | Plasma concentration in Swiss mouse at 2.9 mg/kg, po via gavage administration measured up to 30 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4481292 | A | Plasma concentration in Swiss mouse at 30 mg/kg, po via gavage administration measured at 60 to 120 mins | Mus musculus | 1 | organism-based format | Scientific Literature |
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