# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1909291 | T | FDA Liver Toxicity Knowledge Base Benchmark Dataset (LTKB-BD) drugs of most concern for DILI | 136 | tissue-based format | Scientific Literature | |||
2. | ALA1909321 | A | Drug Induced Liver Injury Prediction System (DILIps) validation dataset; compound DILI positive/negative as observed in LTKB-BD | 73 | tissue-based format | Scientific Literature | |||
3. | ALA1261967 | F | Antiviral activity against Human immunodeficiency virus 1 infected in human assessed as log reduction in HIV-1 RNA level at 600 mg/kg, BID after 10 days | Human immunodeficiency virus 1 | 1 | organism-based format | Scientific Literature | ||
4. | ALA1261968 | T | Hepatotoxicity in rat assessed as increase in liver ALT level at >500 mg/kg/day | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
5. | ALA1261969 | T | Hepatotoxicity in monkey assessed as increase in liver ALT level at 2000 mg/kg/day | Cercopithecidae | 1 | organism-based format | Scientific Literature | ||
6. | ALA1261970 | A | AUC (0 to 24 hrs) in Human immunodeficiency virus 1 infected human at 600 mg/kg, BID | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
7. | ALA1261971 | A | AUC (0 to 24 hrs) in Human immunodeficiency virus 1 infected human at 800 mg/kg, BID | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
8. | ALA1261972 | A | AUC (0 to 24 hrs) in Human immunodeficiency virus 1 infected human at 200 mg/kg, BID | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
9. | ALA1261973 | A | AUC (0 to 24 hrs) in Human immunodeficiency virus 1 infected human at 400 mg/kg, BID | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
10. | ALA1261974 | A | AUC (0 to 24 hrs) in Human immunodeficiency virus 1 infected human at 800 mg/kg, QD | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
11. | ALA1261975 | A | Half life in healthy human at 200 to 800 mg/kg, BID | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
12. | ALA1261976 | T | Hepatotoxicity in rat assessed as increase in liver bilirubin level at >500 mg/kg/day | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
13. | ALA1657386 | F | Antiviral activity against maraviroc-resistant HIV1 isolate CC185 at 100 times IC90 concentration | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
14. | ALA1657387 | F | Antiviral activity against maraviroc-resistant HIV1 isolate CC185 at 10 times IC90 concentration | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
15. | ALA1657388 | F | Antiviral activity against maraviroc-resistant HIV1 isolate CC185 at IC90 concentration | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
16. | ALA2184878 | B | Binding affinity to CCR5 | 10 | single protein format | Scientific Literature | |||
17. | ALA2184882 | P | Lipophilicity, log P of the compound | 22 | small-molecule physicochemical format | Scientific Literature | |||
18. | ALA2184886 | F | Antiviral activity against R5 tropic Human immunodeficiency virus 1 | Human immunodeficiency virus 1 | 1 | organism-based format | Scientific Literature | ||
19. | ALA2184887 | A | Oral bioavailability in monkey | Macaca mulatta | 1 | organism-based format | Scientific Literature | ||
20. | ALA4029349 | T | Liver toxicity in human assessed as induction of drug-induced liver injury by measuring severity class index | Homo sapiens | 929 | assay format | Scientific Literature |