PUBCHEM_BIOASSAY: qHTS for differential inhibitors of proliferation of Plasmodium falciparum line W2. (Class of assay: confirmatory) [Related PubChem assays: 1815 (Assay for Plasmodium falciparum line 7G8), 1877 (Assay for Plasmodium falciparum line D10), 1816 (Assay for Plasmodium falciparum line GB4), 1876 (Assay for Plasmodium falciparum line 7D3), 1828 (Summary assay)]
PUBCHEM_BIOASSAY: Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488774]
Induction of eumelanogenesis assessed as mushroom tyrosinase-mediated simulation of eumelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in absence of glutathione
Induction of eumelanogenesis assessed as mushroom tyrosinase-mediated simulation of eumelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in absence of glutathione and presence of H2O2
Induction of pheomelanogenesis assessed as mushroom tyrosinase-mediated simulation of pheomelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in presence of 0.65 to 3.2 mM of glutathione
Induction of pheomelanogenesis assessed as mushroom tyrosinase-mediated simulation of pheomelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in presence of 0.65 to 3.2 mM of glutathione and H2O2
Inhibition of mushroom tyrosinase-mediated simulation of pheomelanogenesis assessed as oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in presence of 16.3 to 81.3 mM of glutathione
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging