| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1614198 | F | PUBCHEM_BIOASSAY: qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 7G8. (Class of assay: confirmatory) | 717 | ALA1201862 | assay format | PubChem BioAssays | ||
| 2. | ALA1614544 | F | PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) | Homo sapiens | 36,150 | ALA1201862 | assay format | PubChem BioAssays | |
| 3. | ALA1613859 | F | PUBCHEM_BIOASSAY: Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Validation Assay. (Class of assay: confirmatory) [Related pubchem assays: 1705, 1708 ] | 121 | ALA1201862 | assay format | PubChem BioAssays | ||
| 4. | ALA1613914 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) | Homo sapiens | 39,332 | ALA1201862 | assay format | PubChem BioAssays | |
| 5. | ALA1614108 | A | PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] | Homo sapiens | 6,513 | ALA1201862 | single protein format | PubChem BioAssays | |
| 6. | ALA1613767 | F | PUBCHEM_BIOASSAY: qHTS for differential inhibitors of proliferation of Plasmodium falciparum line W2. (Class of assay: confirmatory) [Related PubChem assays: 1815 (Assay for Plasmodium falciparum line 7G8), 1877 (Assay for Plasmodium falciparum line D10), 1816 (Assay for Plasmodium falciparum line GB4), 1876 (Assay for Plasmodium falciparum line 7D3), 1828 (Summary assay)] | 881 | ALA1201862 | assay format | PubChem BioAssays | ||
| 7. | ALA1613886 | A | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] | Homo sapiens | 6,513 | ALA1201862 | single protein format | PubChem BioAssays | |
| 8. | ALA1614045 | F | PUBCHEM_BIOASSAY: Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488774] | Plasmodium falciparum | 390 | ALA1201862 | organism-based format | PubChem BioAssays | |
| 9. | ALA3293511 | B | Induction of eumelanogenesis assessed as mushroom tyrosinase-mediated simulation of eumelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in absence of glutathione | Agaricus bisporus | 1 | ALA3286294 | single protein format | Scientific Literature | |
| 10. | ALA3293512 | B | Induction of eumelanogenesis assessed as mushroom tyrosinase-mediated simulation of eumelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in absence of glutathione and presence of H2O2 | Agaricus bisporus | 1 | ALA3286294 | single protein format | Scientific Literature | |
| 11. | ALA3293513 | B | Induction of pheomelanogenesis assessed as mushroom tyrosinase-mediated simulation of pheomelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in presence of 0.65 to 3.2 mM of glutathione | Agaricus bisporus | 1 | ALA3286294 | single protein format | Scientific Literature | |
| 12. | ALA3293514 | B | Induction of pheomelanogenesis assessed as mushroom tyrosinase-mediated simulation of pheomelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in presence of 0.65 to 3.2 mM of glutathione and H2O2 | Agaricus bisporus | 1 | ALA3286294 | single protein format | Scientific Literature | |
| 13. | ALA3293515 | B | Inhibition of mushroom tyrosinase-mediated simulation of pheomelanogenesis assessed as oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in presence of 16.3 to 81.3 mM of glutathione | Agaricus bisporus | 1 | ALA3286294 | single protein format | Scientific Literature | |
| 14. | ALA4651403 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 4,309 | ALA4651402 | organism-based format | IMI-CARE SARS-CoV-2 Data | |
| 15. | ALA4729511 | F | Inhibition glutathione synthesis in human MIA PaCa-2 cells at 1 to 2 uM measured after 2 to 4 hrs by GSH/GSSG-glo assay | Homo sapiens | 2 | ALA4725371 | cell-based format | Scientific Literature | |
| 16. | ALA4732400 | A | Cytotoxicity against human MCF-10A cells at 200 uM | Homo sapiens | 1 | ALA4732022 | cell-based format | Scientific Literature | |
| 17. | ALA4732408 | B | Inhibition of survivin in human MDA-MB-231 cells assessed as reduction in survivin mRNA expression measured after 72 hrs by qPCR analysis | Homo sapiens | 3 | ALA4732022 | cell-based format | Scientific Literature | |
| 18. | ALA4732409 | B | Inhibition of survivin in human BT-20 cells assessed as reduction in survivin mRNA expression measured after 72 hrs by qPCR analysis | Homo sapiens | 3 | ALA4732022 | cell-based format | Scientific Literature | |
| 19. | ALA4732410 | B | Inhibition of survivin in human MDA-MB-453 cells assessed as reduction in survivin mRNA expression measured after 72 hrs by qPCR analysis | Homo sapiens | 3 | ALA4732022 | cell-based format | Scientific Literature | |
| 20. | ALA4732413 | F | Induction of ROS generation in human MDA-MB-231 cells assessed as increase in ROS level at 1 mM incubated for 12 hrs by DAPI staining based assay | Homo sapiens | 1 | ALA4732022 | cell-based format | Scientific Literature |
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