# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1267179 | B | Displacement of IWP-PB from porcn in HEK293 lysate by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA1267181 | B | Inhibition of porcn-mediated Lrp6 maturation in human DLD1 lysate by detergent solubility fractionation assessed as [3H]palmitate incorporation at 2.5 uM by autoradiography method | Homo sapiens | 1 | assay format | Scientific Literature | ||
3. | ALA1267182 | B | Inhibition of porcn-mediated Shh palmitoylation in human DLD1 lysate by detergent solubility fractionation assessed as [3H]palmitate incorporation at 2.5 uM by autoradiography method | Homo sapiens | 4 | assay format | Scientific Literature | ||
4. | ALA1267183 | B | Inhibition of Notch pathway in HEK293 cells at 2.5 uM | 4 | cell-based format | Scientific Literature | |||
5. | ALA1267299 | B | Inhibition of Wnt3A/beta-casein pathway activity in mouse L cell expressing Wnt3a assessed as inhibition of beta-casein accumulation at 5 uM after 24 hrs by Western blot analysis | 4 | cell-based format | Scientific Literature | |||
6. | ALA1267300 | B | Inhibition of Wnt3A/beta-casein pathway activity in mouse L cell expressing Wnt3a assessed as decrease in phosphorylated Dvl2 level at 5 uM after 24 hrs by Western blot analysis | 4 | cell-based format | Scientific Literature | |||
7. | ALA1267301 | B | Inhibition of Wnt3A/beta-casein pathway activity in mouse L cell expressing Wnt3a assessed as decrease in phosphorylated Lrp6 level at 5 uM after 24 hrs by Western blot analysis | 4 | cell-based format | Scientific Literature | |||
8. | ALA1267306 | F | Inhibition of caudal fin regeneration after mechanical resection in zebrafish at 10 uM after 7 days | Danio rerio | 9 | organism-based format | Scientific Literature | ||
9. | ALA2330993 | B | Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay | Mus musculus | 63 | cell-based format | Scientific Literature | ||
10. | ALA3635400 | B | Inhibition of porcupine activity (unknown origin) expressed in human HT1080 cells assessed as suppression of Wnt3A-mediated super top flash activity by STF luciferase assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
11. | ALA5226909 | B | Inhibition of Wnt/beta-catenin signaling pathway in mouse L Wnt-3A cells harbouring STF-reporter gene assessed as assessed as reduction in luciferase activity incubated for 24 hrs by luciferase reporter assay | Mus musculus | 4 | cell-based format | Scientific Literature |