# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1259548 | B | Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation counting | 46 | cell-based format | Scientific Literature | |||
2. | ALA1259549 | F | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by colorimetric tetrazolium assay | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
3. | ALA2379912 | A | Half life in rat liver microsomes at 3 uM | Rattus norvegicus | 3 | microsome format | Scientific Literature | ||
4. | ALA2379913 | A | Intrinsic clearance in rat liver microsomes at 3 uM | Rattus norvegicus | 3 | microsome format | Scientific Literature | ||
5. | ALA2380122 | A | Permeability of the compound at 5 uM after 16 hrs agitation by PAMPA | 2 | assay format | Scientific Literature | |||
6. | ALA2380123 | P | Aqueous solubility of the compound at pH 7.4 after 24 hrs agitation | 5 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA2380124 | A | Antiproliferative activity against human IMR90 cells after 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA2380126 | F | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA2380127 | F | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
10. | ALA2380128 | F | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
11. | ALA2380129 | B | Inhibition of recombinant Icmt (unknown origin) expressed in Sf9 cells assessed as transfer of methyl group from [3H]-S-adenosylmethionine to [3H]-biotin-S-farnesyl-L-cysteine after 30 mins | Homo sapiens | 19 | cell-based format | Scientific Literature |