# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1273000 | F | Antimalarial activity against erythrocytic stages of chloroquine and pyrimethamine-resistant Plasmodium falciparum K1 assessed as [3H]hypoxanthine incorporation after 48 hrs by liquid scintillation counting | Plasmodium falciparum | 6 | ALA1268887 | organism-based format | Scientific Literature | |
2. | ALA1273001 | F | Antimalarial activity against liver stages of Plasmodium yoelii expressing GFP infected in human HepG2:CD81 cells after 43 hrs by flow cytometry | Plasmodium yoelii | 6 | ALA1268887 | organism-based format | Scientific Literature | |
3. | ALA1273002 | F | Antimalarial activity against liver stages of Plasmodium yoelii expressing GFP infected in human HepG2:CD81 cells after 43 hrs by immunofluorescence analysis | Plasmodium yoelii | 6 | ALA1268887 | organism-based format | Scientific Literature | |
4. | ALA1273003 | A | Cytotoxicity against human HepG2 cells expressing CD81 infected with liver stages of Plasmodium yoelii at up to 25 ug/ml after 43 hrs by DAPI staining | Homo sapiens | 1 | ALA1268887 | cell-based format | Scientific Literature | |
5. | ALA1273004 | B | Inhibition of Plasmodium falciparum FabI by spectrophotometric analysis | Plasmodium falciparum | 6 | ALA1268887 | single protein format | Scientific Literature | |
6. | ALA1273005 | B | Inhibition of Plasmodium falciparum FabZ by spectrophotometric analysis | Plasmodium falciparum | 6 | ALA1268887 | single protein format | Scientific Literature | |
7. | ALA1273006 | B | Inhibition of Plasmodium falciparum FabG by spectrophotometric analysis | Plasmodium falciparum | 6 | ALA1268887 | single protein format | Scientific Literature | |
8. | ALA1273009 | B | Non-competitive inhibition of Plasmodium falciparum FabI using crotonyl-CoA as substrate by Michaelis-Menten steady state analysis | Plasmodium falciparum | 1 | ALA1268887 | single protein format | Scientific Literature | |
9. | ALA1273010 | B | Non-competitive inhibition of Plasmodium falciparum FabI using NADH as cofactor by Michaelis-Menten steady state analysis | Plasmodium falciparum | 1 | ALA1268887 | single protein format | Scientific Literature | |
10. | ALA1273011 | B | Competitive inhibition of Plasmodium falciparum FabZ using crotonyl-CoA as substrate by Michaelis-Menten steady state analysis | Plasmodium falciparum | 1 | ALA1268887 | single protein format | Scientific Literature | |
11. | ALA1273012 | B | Competitive inhibition of Plasmodium falciparum FabG using acetoacetyl-CoA as substrate by Michaelis-Menten steady state analysis | Plasmodium falciparum | 1 | ALA1268887 | single protein format | Scientific Literature | |
12. | ALA1273013 | B | Non-competitive inhibition of Plasmodium falciparum FabG using NADH as cofactor by Michaelis-Menten steady state analysis | Plasmodium falciparum | 1 | ALA1268887 | single protein format | Scientific Literature | |
13. | ALA1273014 | F | Trypanocidal activity against bloodstream form of Trypanosoma brucei rhodesiense STIB 900 after 72 hrs | Trypanosoma brucei rhodesiense | 6 | ALA1268887 | organism-based format | Scientific Literature | |
14. | ALA1273015 | F | Trypanocidal activity against intracellular amastigotes of Trypanosoma cruzi Tulahuen C2C4 expressing LacZ gene infected in rat L6 cells after 96 hrs | Trypanosoma cruzi | 6 | ALA1268887 | organism-based format | Scientific Literature | |
15. | ALA1273016 | F | Leishmanicidal activity against axenic amastigotes of Leishmania donovani MHOM/ET/67/L82 after 72 hrs | Leishmania donovani | 6 | ALA1268887 | organism-based format | Scientific Literature | |
16. | ALA1273017 | A | Cytotoxicity against rat L6 cells after 72 hrs by microplate fluorometric analysis | Rattus norvegicus | 6 | ALA1268887 | cell-based format | Scientific Literature | |
17. | ALA1273018 | B | Inhibition of Mycobacterium tuberculosis inhA | Mycobacterium tuberculosis | 1 | ALA1268887 | single protein format | Scientific Literature | |
18. | ALA2155871 | B | Inhibition of human topoisomerase 1B-mediated relaxation of supercoiled pSK DNA at 100 uM after 4 mins by ethidium bromide staining based agarose gel electrophoresis | Homo sapiens | 1 | ALA2151023 | assay format | Scientific Literature | |
19. | ALA2155873 | F | Antiprotozoal activity against Trypanosoma brucei rhodesiense bloodstream forms | Trypanosoma brucei rhodesiense | 4 | ALA2151023 | organism-based format | Scientific Literature | |
20. | ALA2155874 | F | Antiprotozoal activity against intracellular Trypanosoma cruzi amastigotes in rat L6 cells | Trypanosoma cruzi | 4 | ALA2151023 | organism-based format | Scientific Literature |