# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1273000 | F | Antimalarial activity against erythrocytic stages of chloroquine and pyrimethamine-resistant Plasmodium falciparum K1 assessed as [3H]hypoxanthine incorporation after 48 hrs by liquid scintillation counting | Plasmodium falciparum | 6 | ALA1268887 | organism-based format | Scientific Literature | |
2. | ALA1273001 | F | Antimalarial activity against liver stages of Plasmodium yoelii expressing GFP infected in human HepG2:CD81 cells after 43 hrs by flow cytometry | Plasmodium yoelii | 6 | ALA1268887 | organism-based format | Scientific Literature | |
3. | ALA1273002 | F | Antimalarial activity against liver stages of Plasmodium yoelii expressing GFP infected in human HepG2:CD81 cells after 43 hrs by immunofluorescence analysis | Plasmodium yoelii | 6 | ALA1268887 | organism-based format | Scientific Literature | |
4. | ALA1273004 | B | Inhibition of Plasmodium falciparum FabI by spectrophotometric analysis | Plasmodium falciparum | 6 | ALA1268887 | single protein format | Scientific Literature | |
5. | ALA1273005 | B | Inhibition of Plasmodium falciparum FabZ by spectrophotometric analysis | Plasmodium falciparum | 6 | ALA1268887 | single protein format | Scientific Literature | |
6. | ALA1273006 | B | Inhibition of Plasmodium falciparum FabG by spectrophotometric analysis | Plasmodium falciparum | 6 | ALA1268887 | single protein format | Scientific Literature | |
7. | ALA1273007 | B | Selectivity ratio of IC50 for Plasmodium falciparum FabG to IC50 for Plasmodium falciparum FabI | Plasmodium falciparum | 3 | ALA1268887 | assay format | Scientific Literature | |
8. | ALA1273008 | B | Selectivity ratio of IC50 for Plasmodium falciparum FabG to IC50 for Plasmodium falciparum FabZ | Plasmodium falciparum | 3 | ALA1268887 | assay format | Scientific Literature | |
9. | ALA1273014 | F | Trypanocidal activity against bloodstream form of Trypanosoma brucei rhodesiense STIB 900 after 72 hrs | Trypanosoma brucei rhodesiense | 6 | ALA1268887 | organism-based format | Scientific Literature | |
10. | ALA1273015 | F | Trypanocidal activity against intracellular amastigotes of Trypanosoma cruzi Tulahuen C2C4 expressing LacZ gene infected in rat L6 cells after 96 hrs | Trypanosoma cruzi | 6 | ALA1268887 | organism-based format | Scientific Literature | |
11. | ALA1273016 | F | Leishmanicidal activity against axenic amastigotes of Leishmania donovani MHOM/ET/67/L82 after 72 hrs | Leishmania donovani | 6 | ALA1268887 | organism-based format | Scientific Literature | |
12. | ALA1273017 | A | Cytotoxicity against rat L6 cells after 72 hrs by microplate fluorometric analysis | Rattus norvegicus | 6 | ALA1268887 | cell-based format | Scientific Literature | |
13. | ALA1280432 | F | Antifungal activity against Candida albicans ATCC 14053 at 198.1 uM after 48 hrs by CLSI method | Candida albicans | 1 | ALA1275449 | organism-based format | Scientific Literature | |
14. | ALA1280437 | F | Antifungal activity against Candida albicans ATCC 60193 at 198.1 uM after 48 hrs by CLSI method | Candida albicans | 1 | ALA1275449 | organism-based format | Scientific Literature | |
15. | ALA1280444 | F | Antifungal activity against Candida albicans ATCC 32354 at 198.1 uM after 48 hrs by CLSI method | Candida albicans | 1 | ALA1275449 | organism-based format | Scientific Literature | |
16. | ALA1280592 | F | Antifungal activity against Candida albicans ATCC 90028 at 198.1 uM after 48 hrs by CLSI method | Candida albicans | 1 | ALA1275449 | organism-based format | Scientific Literature | |
17. | ALA1280598 | F | Antifungal activity against Candida albicans ATCC 200955 at 198.1 uM after 48 hrs by CLSI method | Candida albicans | 1 | ALA1275449 | organism-based format | Scientific Literature | |
18. | ALA1280604 | F | Antifungal activity against Fluconazole resistant Candida albicans isolate 1 at 198.1 uM after 48 hrs by CLSI method | Candida albicans | 1 | ALA1275449 | organism-based format | Scientific Literature | |
19. | ALA1280617 | F | Antifungal activity against Candida glabrata ATCC 90030 at 198.1 uM after 48 hrs by CLSI method | Nakaseomyces glabratus | 1 | ALA1275449 | organism-based format | Scientific Literature | |
20. | ALA1280630 | F | Antifungal activity against Candida parapsilosis ATCC 22019 at 198.1 uM after 48 hrs by CLSI method | Candida parapsilosis | 1 | ALA1275449 | organism-based format | Scientific Literature |