# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1273947 | B | Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassay | Mus musculus | 14 | single protein format | Scientific Literature | ||
2. | ALA1273948 | F | Antiasthamatic activity against ovalbumin-induced airway hyperresponsiveness mouse model assessed as reduction of increase in penh value at 30 mg/kg, po administered 24 hrs after last ovalbumin challenge measured after 24 hrs by plethysmography | Mus musculus | 2 | organism-based format | Scientific Literature | ||
3. | ALA1273949 | F | Antiasthamatic activity against ovalbumin-induced airway hyperresponsiveness mouse model assessed as reduction of mononuclear cells infiltration at 30 mg/kg, po measured 48 hrs after ovalbumin challenge | Mus musculus | 2 | organism-based format | Scientific Literature | ||
4. | ALA1274003 | F | Antiasthamatic activity against ovalbumin-induced airway hyperresponsiveness mouse model assessed as reduction of eosinophils infiltration at 30 mg/kg, po measured 48 hrs after ovalbumin challenge | Mus musculus | 2 | organism-based format | Scientific Literature | ||
5. | ALA1274004 | F | Antiasthamatic activity against ovalbumin-induced airway hyperresponsiveness mouse model assessed as reduction of plasma IgE level at 30 mg/kg, po measured 48 hrs after ovalbumin challenge (Rvb = 41.82 +/- 10.57 ng/ml) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
6. | ALA1274005 | F | Antiasthamatic activity against ovalbumin-induced airway hyperresponsiveness mouse model assessed as reduction of bronchoalveolar lavage fluid IL-4 level at 30 mg/kg, po measured 48 hrs after ovalbumin challenge | Mus musculus | 2 | organism-based format | Scientific Literature | ||
7. | ALA1274006 | F | Antiasthamatic activity against ovalbumin-induced airway hyperresponsiveness mouse model assessed as reduction of bronchoalveolar lavage fluid IL-5 level at 30 mg/kg, po measured 48 hrs after ovalbumin challenge | Mus musculus | 2 | organism-based format | Scientific Literature | ||
8. | ALA1274007 | F | Antiasthamatic activity against ovalbumin-induced airway hyperresponsiveness mouse model assessed as reduction of bronchoalveolar lavage fluid IL-13 level at 30 mg/kg, po measured 48 hrs after ovalbumin challenge | Mus musculus | 2 | organism-based format | Scientific Literature |