# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1274996 | B | Inhibition of PHLPP in human HT20 cells assessed as increase of phosphorylation of FoxO1/3alpha on Thr 24/32 at 100 to 250 uM after 24 hrs by immunoblotting | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA1274997 | B | Inhibition of PHLPP in human HT20 cells assessed as increase of phosphorylation of GSK3 alpha/beta on Ser21/9 at 100 to 250 uM after 24 hrs by immunoblotting | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
3. | ALA1275001 | B | Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coli | 31 | assay format | Scientific Literature | |||
4. | ALA1275002 | B | Inhibition of PHLPP in human HT20 cells assessed as increase of phosphorylation of Akt on Ser 473 at 100 to 250 uM after 24 hrs by immunoblotting relative to control | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
5. | ALA1275008 | B | Inhibition of PHLPP expressed in 24 hrs serum starved Cos7 cells assessed as increase of Akt phosphorylation on Ser473 at up to 120 uM after 30 mins by immunoblotting | 2 | cell-based format | Scientific Literature | |||
6. | ALA1275010 | B | Inhibition of PHLPP expressed in 24 hrs serum starved Cos7 cells assessed as half maximal increase of phosphorylation on Ser473 after 30 mins by immunoblotting | 2 | cell-based format | Scientific Literature | |||
7. | ALA1275013 | B | Inhibition of PHLPP expressed in 24 hrs serum starved Cos7 cells assessed as increase of Akt phosphorylation after 30 mins by immunoblotting | 2 | cell-based format | Scientific Literature | |||
8. | ALA1275119 | F | Cytoprotective activity against etoposide-induced cell death in african green monkey COS7 cells at 50 uM after 24 hrs by trypan blue exclusion assay | Chlorocebus aethiops | 2 | cell-based format | Scientific Literature |