# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1274996 | B | Inhibition of PHLPP in human HT20 cells assessed as increase of phosphorylation of FoxO1/3alpha on Thr 24/32 at 100 to 250 uM after 24 hrs by immunoblotting | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA1274997 | B | Inhibition of PHLPP in human HT20 cells assessed as increase of phosphorylation of GSK3 alpha/beta on Ser21/9 at 100 to 250 uM after 24 hrs by immunoblotting | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
3. | ALA1275001 | B | Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coli | 31 | assay format | Scientific Literature | |||
4. | ALA1275002 | B | Inhibition of PHLPP in human HT20 cells assessed as increase of phosphorylation of Akt on Ser 473 at 100 to 250 uM after 24 hrs by immunoblotting relative to control | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
5. | ALA1275120 | A | Cytotoxicity against human HT-29 cells at 100 uM after 24 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature |