# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1281212 | Binding | Inhibition of Staphylococcus aureus wild-type RNA polymerase RpoB | Staphylococcus aureus | 2 | ALA1275434 | assay format | Scientific Literature | |
2. | ALA1281213 | Binding | Inhibition of Staphylococcus aureus RpoB H481Y mutant | Staphylococcus aureus | 2 | ALA1275434 | assay format | Scientific Literature | |
3. | ALA1281214 | Binding | Activity at Staphylococcus aureus wild-type DNA topoisomerase 4 subunit ParC | Staphylococcus aureus | 4 | ALA1275434 | assay format | Scientific Literature | |
4. | ALA1281215 | Binding | Activity at Staphylococcus aureus DNA topoisomerase 4 subunit ParC S80F mutant | Staphylococcus aureus | 4 | ALA1275434 | assay format | Scientific Literature | |
5. | ALA1281216 | Binding | Activity at Staphylococcus aureus wild-type GyrA | Staphylococcus aureus | 4 | ALA1275434 | assay format | Scientific Literature | |
6. | ALA1281217 | Binding | Activity at Staphylococcus aureus wild-type GyrA S84L mutant | Staphylococcus aureus | 4 | ALA1275434 | assay format | Scientific Literature | |
7. | ALA1281218 | Binding | Ratio of CC50 for wild-type Staphylococcus aureus GyrA to CC50 for wild-type Staphylococcus aureus ParC | Staphylococcus aureus | 4 | ALA1275434 | assay format | Scientific Literature | |
8. | ALA1281219 | Binding | Ratio of CC50 for Staphylococcus aureus ParC S80F mutant to CC50 for wild-type Staphylococcus aureus ParC | Staphylococcus aureus | 4 | ALA1275434 | assay format | Scientific Literature | |
9. | ALA1281361 | Functional | Antimicrobial activity against Staphylococcus aureus CB190 by broth microdilution method | Staphylococcus aureus | 6 | ALA1275434 | organism-based format | Scientific Literature | |
10. | ALA1281362 | Functional | Antimicrobial activity against Staphylococcus aureus CB811 harboring quinolone-resistant gyrA S84L mutant gene by broth microdilution method | Staphylococcus aureus | 6 | ALA1275434 | organism-based format | Scientific Literature | |
11. | ALA1281363 | Functional | Antimicrobial activity against Staphylococcus aureus CB808 harboring quinolone-resistant parC S80F mutant gene by broth microdilution method | Staphylococcus aureus | 6 | ALA1275434 | organism-based format | Scientific Literature | |
12. | ALA1281364 | Functional | Antimicrobial activity against Staphylococcus aureus CB814 harboring fluoroquinolone-resistant gyrA S84L and parC S80F mutant genes by broth microdilution method | Staphylococcus aureus | 6 | ALA1275434 | organism-based format | Scientific Literature | |
13. | ALA1281365 | Functional | Antimicrobial activity against Staphylococcus aureus CB370 harboring rifampin-resistant rpoB H481Y mutant gene by broth microdilution method | Staphylococcus aureus | 6 | ALA1275434 | organism-based format | Scientific Literature | |
14. | ALA1281366 | Functional | Antimicrobial activity against Staphylococcus aureus CB812 harboring rpo B H481Y and gyrA S84L mutant genes by broth microdilution method | Staphylococcus aureus | 6 | ALA1275434 | organism-based format | Scientific Literature | |
15. | ALA1281367 | Functional | Antimicrobial activity against Staphylococcus aureus CB812 harboring rpoB H481Y and gyrA S80F mutant genes by broth microdilution method | Staphylococcus aureus | 6 | ALA1275434 | organism-based format | Scientific Literature | |
16. | ALA1281368 | Functional | Antimicrobial activity against Staphylococcus aureus CB812 harboring rpoB H481Y, gyrA S84L and gyrA S80F mutant genes by broth microdilution method | Staphylococcus aureus | 6 | ALA1275434 | organism-based format | Scientific Literature | |
17. | ALA1281373 | Functional | Inhibition of DNA synthesis in Staphylococcus aureus CB190 assessed as decrease in [methyl-3H]thymidine incorporation at 0.5 ug/ml | Staphylococcus aureus | 1 | ALA1275434 | organism-based format | Scientific Literature | |
18. | ALA1281374 | Functional | Inhibition of RNA synthesis in Staphylococcus aureus CB190 assessed as decrease in [5,6-3H]uridine incorporation at 0.5 ug/ml | Staphylococcus aureus | 1 | ALA1275434 | organism-based format | Scientific Literature | |
19. | ALA1281375 | Functional | Inhibition of protein synthesis in Staphylococcus aureus CB190 assessed as decrease in L-[3,4,5-3H]leucine incorporation at 0.5 ug/ml | Staphylococcus aureus | 1 | ALA1275434 | organism-based format | Scientific Literature | |
20. | ALA1281376 | Functional | Inhibition of cell wall synthesis in Staphylococcus aureus CB190 assessed as decrease in [2,3-3H]D-alanine incorporation at 0.5 ug/ml | Staphylococcus aureus | 1 | ALA1275434 | organism-based format | Scientific Literature |