| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1287092 | F | Ex vivo displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat cerebral cortex at 1 mg/kg, po by imaging analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA1287093 | F | Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assay | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 3. | ALA1287094 | F | Antagonist activity at human 5HT2A receptor expressed in HEK cells assessed as inhibition of intracellular calcium accumulation by aequorin assay | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 4. | ALA1287095 | F | Antagonist activity at human 5HT2B receptor expressed in human SH-SY5Y cells by FLIPR assay | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 5. | ALA1287096 | F | Antagonist activity at human 5HT2C receptor expressed in human SH-SY5Y cells by FLIPR assay | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 6. | ALA1287098 | B | Displacement of [3H]dofetilide from human ERG by scintillation proximity assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 7. | ALA1287099 | B | Displacement of [3H]pyrilamine from histamine H1 receptor in Sprague-Dawley rat cortical membrane by liquid scintillation counting | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
| 8. | ALA1287100 | B | Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat cortical membrane by liquid scintillation counting | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
| 9. | ALA1287101 | A | Intrinsic clearance in rat liver microsomes assessed per gram of liver after 30 mins by HPLC/MS/MS analysis | Rattus norvegicus | 7 | microsome format | Scientific Literature | ||
| 10. | ALA1287102 | A | Intrinsic clearance in human liver microsomes assessed per gram of liver after 30 mins by HPLC/MS/MS analysis | Homo sapiens | 7 | microsome format | Scientific Literature | ||
| 11. | ALA1287103 | A | Inhibition of human CYP1A2 transfected in bactosome expression system by spectrofluorimetry | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 12. | ALA1287104 | A | Inhibition of human CYP2C9 transfected in bactosome expression system by spectrofluorimetry | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 13. | ALA1287105 | A | Inhibition of human CYP2C19 transfected in bactosome expression system by spectrofluorimetry | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 14. | ALA1287106 | A | Inhibition of human CYP2D6 transfected in bactosome expression system by spectrofluorimetry | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 15. | ALA1287107 | A | Inhibition of human CYP3A4 transfected in bactosome expression system by spectrofluorimetry | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 16. | ALA1287108 | A | Fraction unbound in rat brain | Rattus norvegicus | 7 | tissue-based format | Scientific Literature | ||
| 17. | ALA1287109 | A | Fraction unbound in rat blood | Rattus norvegicus | 7 | tissue-based format | Scientific Literature | ||
| 18. | ALA1287111 | A | Blood clearance in Sprague-Dawley rat at 1 mg/kg, iv and 3 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 19. | ALA1287113 | A | Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv and 3 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 20. | ALA1287115 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv and 3 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature |
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