# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1285620 | Binding | Inhibition of GluR4 expressed in HEK293 cells | 9 | ALA1275320 | cell-based format | Scientific Literature | ||
2. | ALA4303805 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
3. | ALA4303806 | Functional | Determination of IC50 values for inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells after 48 hours by high content imaging | Homo sapiens | 67 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
4. | ALA4303807 | Toxicity | Toxicity against Caco-2 cells determined at 48 hours by intracellular ATP concentration using the CellTiter-Glo Luminescent Cell Viability Assay | Homo sapiens | 67 | ALA4303101 | cell-based format | SARS-CoV-2 Screening Data 2020-21 | |
5. | ALA4303808 | Toxicity | Cytotoxicity index (CI): selectivity for inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells versus toxicity against Caco-2 cells (CC50/IC50) | Homo sapiens | 67 | ALA4303101 | cell-based format | SARS-CoV-2 Screening Data 2020-21 | |
6. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
7. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
8. | ALA4808149 | Binding | Enzymatic assay of human HDAC6 with commercial peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 | |
9. | ALA4808150 | Binding | Enzymatic assay of human HDAC6 with custom peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 |