| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1285468 | B | Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 mins | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 2. | ALA1285470 | B | Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 mins | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 3. | ALA1285472 | B | Selectivity ratio of IC50 for human placenta 17beta-HSD2 to IC50 for human placenta 17beta-HSD1 | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 4. | ALA1285474 | B | Displacement of [2,4,6,7-3H]-17beta-estradiol from ERalpha after 1 hr relative to estradiol | 24 | single protein format | Scientific Literature | |||
| 5. | ALA1285475 | B | Displacement of [2,4,6,7-3H]-17beta-estradiol from ERbeta after 1 hr relative to estradiol | 24 | single protein format | Scientific Literature | |||
| 6. | ALA3300201 | B | Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate at 1 uM after 10 mins by HPLC analysis relative to control | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 7. | ALA3300202 | B | Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate at 1 uM after 20 mins by HPLC analysis relative to control | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 8. | ALA3300203 | B | Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysis | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 9. | ALA3300204 | B | Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 10. | ALA3300205 | B | Selectivity factor, ratio of IC50 for human placental 17beta-HSD2 microsomal fraction to IC50 for human placental 17beta-HSD1 cytosolic fraction | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 11. | ALA3300206 | B | Inhibition of recombinant mouse 17beta-HSD1 expressed in HEK293 cells using [3H]-estrone as substrate at 1 uM after 10 mins by HPLC analysis relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA3631240 | B | Inhibition of human placental cytosolic 17beta HSD1 using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins by HPLC analysis | Homo sapiens | 49 | assay format | Scientific Literature | ||
| 13. | ALA3631243 | B | Inhibition of recombinant mouse 17beta HSD1 expressed in HEK293 cells using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate at 1 uM incubated for 10 mins by HPLC analysis | Mus musculus | 47 | cell-based format | Scientific Literature |
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