| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1286450 | B | Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiology assay | Rattus norvegicus | 19 | ALA1275385 | tissue-based format | Scientific Literature | |
| 2. | ALA1286451 | B | Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assay | Mus musculus | 23 | ALA1275385 | cell-based format | Scientific Literature | |
| 3. | ALA1286452 | B | Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltage clamp electrophysiology assay | Homo sapiens | 20 | ALA1275385 | cell-based format | Scientific Literature | |
| 4. | ALA1286453 | B | Inhibition of human recombinant NaV1.2 by electrophysiology | Homo sapiens | 16 | ALA1275385 | single protein format | Scientific Literature | |
| 5. | ALA1286455 | P | Aqueous solubility of the compound | 18 | ALA1275385 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA1286457 | B | Selectivity ratio of IC50 for human NAv1.8 to IC50 for human Nav1.2 | Homo sapiens | 5 | ALA1275385 | assay format | Scientific Literature | |
| 7. | ALA1286458 | B | Selectivity ratio of IC50 for tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons to IC50 for human Nav1.2 | 2 | ALA1275385 | tissue-based format | Scientific Literature |
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