# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1641185 | Binding | Selectivity for Trypanosoma cruzi triosephosphate isomerase over human triosephosphate isomerase | 226 | ALA1629474 | assay format | Scientific Literature | ||
2. | ALA1641186 | Functional | Antiparasitic activity against Trypanosoma cruzi T2 epimastigotes assessed as growth inhibition | Trypanosoma cruzi | 15 | ALA1629474 | organism-based format | Scientific Literature | |
3. | ALA1641187 | Functional | Antiparasitic activity against Trypanosoma cruzi T2 epimastigotes assessed as growth inhibition at 25 uM after 5 days | Trypanosoma cruzi | 227 | ALA1629474 | organism-based format | Scientific Literature | |
4. | ALA1641188 | Binding | Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrs | Trypanosoma cruzi | 5 | ALA1629474 | single protein format | Scientific Literature | |
5. | ALA1641189 | Binding | Inhibition of Trypanosoma cruzi triosephosphate isomerase at 100 uM after 2 hrs | Trypanosoma cruzi | 227 | ALA1629474 | single protein format | Scientific Literature | |
6. | ALA1641190 | Binding | Inhibition of Trypanosoma cruzi triosephosphate isomerase at 400 uM after 2 hrs | Trypanosoma cruzi | 227 | ALA1629474 | single protein format | Scientific Literature | |
7. | ALA1641191 | Binding | Inhibition of human triosephosphate isomerase at 100 uM after 2 hrs | Homo sapiens | 5 | ALA1629474 | single protein format | Scientific Literature | |
8. | ALA1641192 | Functional | Antiparasitic activity against Trypanosoma cruzi Y epimastigotes assessed as growth inhibition at 25 uM after 5 days | Trypanosoma cruzi | 1 | ALA1629474 | organism-based format | Scientific Literature | |
9. | ALA1641193 | Functional | Antiparasitic activity against Trypanosoma cruzi Y epimastigotes assessed as growth inhibition | Trypanosoma cruzi | 1 | ALA1629474 | organism-based format | Scientific Literature | |
10. | ALA1641194 | Functional | Antiparasitic activity against Trypanosoma cruzi CLB epimastigotes assessed as growth inhibition at 25 uM after 5 days | Trypanosoma cruzi | 3 | ALA1629474 | organism-based format | Scientific Literature | |
11. | ALA1641195 | Functional | Antiparasitic activity against Trypanosoma cruzi CLB epimastigotes assessed as growth inhibition | Trypanosoma cruzi | 3 | ALA1629474 | organism-based format | Scientific Literature | |
12. | ALA1292792 | Binding | Binding affinity to calf thymus DNA assessed as ratio of final absorbance area to absorbance of compound at 100 uM after 24 hrs by UV spectrophotometer analysis | Bos taurus | 14 | ALA1287653 | nucleic acid format | Scientific Literature | |
13. | ALA1292794 | ADME | Cytotoxicity against chinese hamster V79 cells assessed as survival fraction under normoxic condition at 20 uM after 7 days by crystal violet staining relative to control | Cricetulus griseus | 13 | ALA1287653 | cell-based format | Scientific Literature | |
14. | ALA1292795 | ADME | Cytotoxicity against chinese hamster V79 cells assessed as survival fraction under normoxic condition at 10 uM after 7 days by crystal violet staining relative to control | Cricetulus griseus | 3 | ALA1287653 | cell-based format | Scientific Literature | |
15. | ALA1292796 | Functional | Cytotoxicity against chinese hamster V79 cells assessed as survival fraction under hypoxic condition at 20 uM after 7 days by crystal violet staining relative to control | Cricetulus griseus | 13 | ALA1287653 | cell-based format | Scientific Literature | |
16. | ALA1292797 | Functional | Cytotoxicity against chinese hamster V79 cells assessed as survival fraction under hypoxic condition at 10 uM after 7 days by crystal violet staining relative to control | Cricetulus griseus | 3 | ALA1287653 | cell-based format | Scientific Literature |