| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1292492 | F | Antagonist activity at human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells assessed as inhibition of (S)-glutamate/glycine-stimulated excitotoxicity treated 30 mins before (S)-glutamate/glycine challenge measured after 4 hrs by LDH release assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA1292493 | F | Antagonist activity at human recombinant NR1-1a/NR2A receptor expressed in mouse L12-G10 cells assessed as inhibition of (S)-glutamate/glycine-stimulated excitotoxicity at 10 uM treated 30 mins before (S)-glutamate/glycine challenge measured after 4 hrs by LDH release assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA1292494 | B | Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation counting | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 4. | ALA1292495 | F | Analgesic activity in mouse assessed reduction formalin-induced acute pain at 10 to 100 mg/kg, ip administered 30 mins before formalin challenge measured after 10 to 35 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA1292496 | B | Displacement of [3H]-Ifenprodil from polyamine transporter at 1 to 3 uM | 1 | assay format | Scientific Literature | |||
| 6. | ALA1292497 | B | Displacement of [3H]-(+)-MK 801 from NMDA receptor phencyclidine binding site in pig brain cortex after 150 mins by scintillation counting | Sus scrofa | 30 | assay format | Scientific Literature | ||
| 7. | ALA1292498 | B | Displacement of [3H](+)-pentazocine from sigma1 receptor guinea pig brain after 180 mins scintillation counting | Cavia porcellus | 32 | assay format | Scientific Literature | ||
| 8. | ALA1292499 | B | Displacement of [3H]di-o-tolylguanidine from sigma2 receptor rat liver membranes after 180 mins scintillation counting | Rattus norvegicus | 32 | cell membrane format | Scientific Literature | ||
| 9. | ALA1292501 | B | Selectivity ratio of Ki for human recombinant NR1a/NR2B receptor to Ki for guinea pig sigma1 receptor | 5 | assay format | Scientific Literature | |||
| 10. | ALA1292502 | A | Half life in mouse liver microsomes | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 11. | ALA1292503 | A | Half life in rat liver microsomes | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
| 12. | ALA1292504 | A | Half life in human liver microsomes | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 13. | ALA1292505 | T | Toxicity in mouse assessed as unusual reactions at 1 to 100 mg/kg, ip after 24 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA1292506 | T | Toxicity in mouse assessed as diarrhea at 100 mg/kg, ip after 30 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA1292507 | F | Analgesic activity in ip dosed mouse assessed as decrease in von Frey filament-induced neuropathic pain | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA1292508 | F | Analgesic activity in mouse assessed as decrease in von Frey filament-induced neuropathic pain at 30 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA1292509 | F | Analgesic activity in mouse assessed as decrease in von Frey filament-induced neuropathic pain at 10 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA1292510 | B | Displacement of [3H]-DPCPX from adenosine A1 receptor at 1 to 3 uM | 1 | single protein format | Scientific Literature | |||
| 19. | ALA1292511 | B | Displacement of [3H]-CGS-21680 from adenosine A2A receptor at 1 to 3 uM | 1 | single protein format | Scientific Literature | |||
| 20. | ALA1292512 | B | Displacement of [125I]-AB-MECA from adenosine A3 receptor at 1 to 3 uM | 1 | single protein format | Scientific Literature |
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