| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1291825 | B | Inhibition of COX-2 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs in by HPLC presence of calcium ionophore A23188 and lipopolysaccharide | Oryctolagus cuniculus | 16 | tissue-based format | Scientific Literature | ||
| 2. | ALA1291826 | B | Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of calcium ionophore A23187 | Oryctolagus cuniculus | 16 | single protein format | Scientific Literature | ||
| 3. | ALA1291827 | B | Inhibition of 5-LOX in rabbit peripheral venous blood assessed as formation of LBT4 after 30 mins by HPLC | Oryctolagus cuniculus | 16 | tissue-based format | Scientific Literature | ||
| 4. | ALA1291828 | B | Selectivity ratio, IC50 for COX-1in rabbit peripheral venous blood to IC50 for COX-2 in rabbit peripheral venous blood | Oryctolagus cuniculus | 16 | tissue-based format | Scientific Literature | ||
| 5. | ALA1291882 | F | Antiinflammatory activity in Wistar rat assessed as inhibition of carrageenan-induced paw edema at 10.15 mg/kg, po administered 1 hr before carrageenan challenge measured at 1 hr by plethysmometer | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA1291883 | F | Antiinflammatory activity in Wistar rat assessed as inhibition of carrageenan-induced paw edema at 10.15 mg/kg, po administered 1 hr before carrageenan challenge measured at 3 hrs by plethysmometer | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA1291884 | F | Antiinflammatory activity in Wistar rat assessed as inhibition of carrageenan-induced paw edema at 10.15 mg/kg, po administered 1 hr before carrageenan challenge measured at 6 hrs by plethysmometer | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA1291903 | F | Analgesic activity in BALB/c mouse assessed as inhibition of acetic acid-induced writhing response for 15 mins at 20.30 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA1291919 | T | Ulcerogenic effect in Wistar rat assessed as gastric ulcer area at 10.15 mg/kg, po administered for 7 days by microscopy | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
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