| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA630098 | P | Partition coefficient (logP) | 28 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA634455 | A | In vitro clearance in dog in 1000000 cells | Canis lupus familiaris | 17 | organism-based format | Scientific Literature | ||
| 3. | ALA634457 | A | In vitro clearance in human in 1000000 cells | Homo sapiens | 19 | organism-based format | Scientific Literature | ||
| 4. | ALA634458 | A | In vitro clearance in rat in 1000000 cells | Rattus norvegicus | 19 | organism-based format | Scientific Literature | ||
| 5. | ALA634460 | A | In vivo clearance in dog. | Canis lupus familiaris | 7 | organism-based format | Scientific Literature | ||
| 6. | ALA635503 | A | In vivo clearance in human. | Homo sapiens | 8 | organism-based format | Scientific Literature | ||
| 7. | ALA635505 | A | In vivo clearance in rat. | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 8. | ALA636394 | A | Delta logD (logD6.5 - logD7.4) | 152 | assay format | Scientific Literature | |||
| 9. | ALA646647 | P | Partition coefficient (logD6.5) | 153 | small-molecule physicochemical format | Scientific Literature | |||
| 10. | ALA645153 | P | Ionization constant (pKa) | 204 | small-molecule physicochemical format | Scientific Literature | |||
| 11. | ALA633100 | A | Oral bioavailability in human | Homo sapiens | 46 | organism-based format | Scientific Literature | ||
| 12. | ALA659156 | F | In vitro inhibition of alpha-1G T-type [Ca2+] channels expressed in HEK293 cells at 10 uM | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 13. | ALA654651 | F | In vitro inhibitory effect on alpha-1H T-type [Ca2+] channels expressed in Xenopus oocytes at 100 uM | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 14. | ALA656375 | F | K+ channel blocking activity in COS-7 African green monkey kidney derived cells expressing HERG Kv11.1 | 1 | cell-based format | Scientific Literature | |||
| 15. | ALA664809 | A | Inhibition of human cytochrome P450 3A4 | 28 | single protein format | Scientific Literature | |||
| 16. | ALA689508 | F | Concentration of the compounds required for inhibition of HEK293 cells (alpha1G T-type) | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 17. | ALA755826 | F | Inhibition of P-glycoprotein using ATPase in MDR1 membranes | 28 | cell membrane format | Scientific Literature | |||
| 18. | ALA755827 | F | Inhibition of P-glycoprotein, human L-MDR1 expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay | 28 | cell-based format | Scientific Literature | |||
| 19. | ALA755828 | F | Inhibition of P-glycoprotein, mouse L-mdr1a expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay | 28 | cell-based format | Scientific Literature | |||
| 20. | ALA754159 | F | Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay | 28 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!