| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA838886 | B | Compound was tested for inhibition activity against Coagulation factor X | 39 | single protein format | Scientific Literature | |||
| 2. | ALA661794 | B | Inhibitory potency was measured against human coagulation factor X | 32 | single protein format | Scientific Literature | |||
| 3. | ALA813659 | B | Compound was tested for inhibition activity against human thrombin (FIIa) | 37 | single protein format | Scientific Literature | |||
| 4. | ALA813627 | B | Inhibitory potency was measured against human thrombin | 31 | single protein format | Scientific Literature | |||
| 5. | ALA817573 | B | Compound was tested for inhibition activity against bovine trypsin. | Bos taurus | 37 | single protein format | Scientific Literature | ||
| 6. | ALA817592 | B | Inhibitory potency was measured against bovine trypsin. | Bos taurus | 30 | single protein format | Scientific Literature | ||
| 7. | ALA3101477 | B | Inhibition of thrombin (unknown origin) by fluorescence assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
| 8. | ALA3101478 | B | Inhibition of trypsin (unknown origin) by fluorescence assay | Homo sapiens | 11 | protein format | Scientific Literature | ||
| 9. | ALA3101479 | B | Inhibition of factor 10a (unknown origin) using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrate | Homo sapiens | 11 | single protein format | Scientific Literature | ||
| 10. | ALA3101481 | B | Inhibition of matriptase-SP1 (615 to 855) (unknown origin) expressed in Escherichia coli BL21(DE3) using Boc-Gln-Ala-Arg-7-amido-4-methyl coumarin hydrobromide as substrate by fluorescence assay | Homo sapiens | 14 | assay format | Scientific Literature | ||
| 11. | ALA4827162 | A | Cytotoxicity against rat L6 cells by Alamar blue assay | Rattus norvegicus | 16 | cell-based format | Scientific Literature | ||
| 12. | ALA4827163 | B | Binding affinity to poly (dA-dT) (unknown origin) assessed as thermal stability by measuring change in melting temperature | Not specified | 10 | nucleic acid format | Scientific Literature | ||
| 13. | ALA4827164 | F | Antitrypanosomal activity against Trypanosoma brucei rhodesiense STIB900 measured after 72 hrs by alamar blue dye based fluorimetry analysis | Trypanosoma brucei rhodesiense | 16 | organism-based format | Scientific Literature | ||
| 14. | ALA4827165 | F | Antiplasmodial activity against chloroquine and pyrimethamine resistant Plasmodium falciparum K1 infected in human erythrocytes assessed as reduction in [3H]hypoxanthine incorporation measured after 24 hrs by liquid scintillation counting method | Plasmodium falciparum | 16 | organism-based format | Scientific Literature | ||
| 15. | ALA4827166 | T | Selectivity index, ratio of IC50 for cytotoxicity against rat L6 cells to IC50 for antitrypanosomal activity against Trypanosoma brucei rhodesiense STIB900 | 16 | cell-based format | Scientific Literature | |||
| 16. | ALA4827167 | T | Selectivity index, ratio of IC50 for cytotoxicity against rat L6 cells to IC50 for antiplasmodial activity against chloroquine and pyrimethamine resistant Plasmodium falciparum K1 infected in human red blood cells | 16 | cell-based format | Scientific Literature | |||
| 17. | ALA4827168 | F | Antitrypanosomal activity against bloodstream form of Trypanosoma brucei rhodesiense STIB900 infected in mouse assessed as reduction in parasitemia by measuring time taken to cure at 5 mg/kg, ip measured up to 60 days (Rvb = 11 days) | Trypanosoma brucei rhodesiense | 10 | organism-based format | Scientific Literature |
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