# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA629148 | P | Log P value by using Octanol / pH 7.4 buffer | 9 | ALA1127561 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA645541 | B | In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparation | 27 | ALA1127561 | single protein format | Scientific Literature | ||
3. | ALA645284 | B | Compound was evaluated In vitro for inhibition of aldose reductase activity by 50% in dog RBC | Canis lupus familiaris | 3 | ALA1127561 | single protein format | Scientific Literature | |
4. | ALA645593 | B | Compound was evaluated In vitro for inhibition of aldose reductase activity by 50% in rat RBC | 2 | ALA1127561 | assay format | Scientific Literature | ||
5. | ALA780784 | F | Dose at which the tissue level of polyol accumulation was reduced by 50% was evaluated for 14 days in RBC | Rattus norvegicus | 2 | ALA1127561 | organism-based format | Scientific Literature | |
6. | ALA780785 | F | Dose at which the tissue level of polyol accumulation was reduced by 50% was evaluated for 14 days in lens | Rattus norvegicus | 1 | ALA1127561 | organism-based format | Scientific Literature | |
7. | ALA780786 | F | Dose at which the tissue level of polyol accumulation was reduced by 50% was evaluated for 14 days in sciatic nerve | Rattus norvegicus | 2 | ALA1127561 | organism-based format | Scientific Literature | |
8. | ALA780787 | F | Dose at which the tissue level of polyol accumulation was reduced by 50% was evaluated for 4 days in lens | Rattus norvegicus | 2 | ALA1127561 | organism-based format | Scientific Literature | |
9. | ALA780788 | F | Dose at which the tissue level of polyol accumulation was reduced by 50% was evaluated for 4 days in sciatic nerve | Rattus norvegicus | 2 | ALA1127561 | organism-based format | Scientific Literature | |
10. | ALA789951 | F | Percentage Inhibition of galactitol accumulation in the lens of rats fed with the dose of 1.1 mg/kg/day; NS=Not significant | Rattus norvegicus | 1 | ALA1127561 | organism-based format | Scientific Literature | |
11. | ALA794565 | F | Percentage Inhibition of galactitol accumulation in the lens of rats fed with the dose of 4.0 mg/kg/day; NS=Not significant | Rattus norvegicus | 1 | ALA1127561 | organism-based format | Scientific Literature | |
12. | ALA794566 | F | Percentage Inhibition of galactitol accumulation in the sciatic nerve of rats fed with the dose of 0.5 mg/kg/day | Rattus norvegicus | 15 | ALA1127561 | organism-based format | Scientific Literature | |
13. | ALA790065 | F | Percentage Inhibition of galactitol accumulation in the sciatic nerve of rats fed with the dose of 1.1 mg/kg/day | Rattus norvegicus | 2 | ALA1127561 | organism-based format | Scientific Literature | |
14. | ALA790068 | F | Percentage Inhibition of galactitol accumulation in the sciatic nerve of rats fed with the dose of 4.0 mg/kg/day | Rattus norvegicus | 1 | ALA1127561 | organism-based format | Scientific Literature | |
15. | ALA924228 | B | Inhibition of aldose reductase | 28 | ALA1140501 | single protein format | Scientific Literature | ||
16. | ALA936590 | B | Inhibition of mouse recombinant AKR1C21 | Mus musculus | 6 | ALA1143916 | single protein format | Scientific Literature | |
17. | ALA936594 | B | Inhibition of human recombinant aldose reductase | Homo sapiens | 9 | ALA1143916 | single protein format | Scientific Literature | |
18. | ALA1023734 | B | Inhibition of human recombinant ALR2 expressed in bacterial cell expression system by Uncompetitive inhibition based Lineweaver-Burke plot | Homo sapiens | 4 | ALA1143335 | assay format | Scientific Literature | |
19. | ALA1023735 | B | Inhibition of pig ALR1 | Sus scrofa | 4 | ALA1143335 | single protein format | Scientific Literature | |
20. | ALA1023736 | B | Inhibition of human recombinant ALR2 expressed in bacterial cell expression system | Homo sapiens | 4 | ALA1143335 | assay format | Scientific Literature |