# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3758003 | Binding | Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Mycobacterium tuberculosis | 40 | ALA3751721 | assay format | Scientific Literature | |
2. | ALA3758004 | Binding | Inhibition of Mycobacterium smegmatis GyrB by ATPase assay | Mycolicibacterium smegmatis | 36 | ALA3751721 | single protein format | Scientific Literature | |
3. | ALA3758005 | Binding | Inhibition of Staphylococcus aureus DNA gyrase assessed as inhibition of DNA supercoiling | Staphylococcus aureus | 36 | ALA3751721 | protein complex format | Scientific Literature | |
4. | ALA3758006 | Binding | Inhibition of Escherichia coli DNA gyrase assessed as inhibition of DNA supercoiling | Escherichia coli | 36 | ALA3751721 | assay format | Scientific Literature | |
5. | ALA3758007 | Binding | Inhibition of Pseudomonas aeruginosa DNA gyrase assessed as inhibition of DNA supercoiling | Pseudomonas aeruginosa | 36 | ALA3751721 | protein complex format | Scientific Literature | |
6. | ALA3758008 | Binding | Inhibition of Mycobacterium tuberculosis DNA topoisomerase 1 assessed as DNA relaxation at 50 uM | Mycobacterium tuberculosis | 36 | ALA3751721 | assay format | Scientific Literature | |
7. | ALA3758010 | Functional | Antimicrobial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 28 days by alamar blue assay | Mycobacterium tuberculosis | 40 | ALA3751721 | organism-based format | Scientific Literature | |
8. | ALA3758011 | ADME | Cytotoxicity against mouse RAW264.7 cells assessed as inhibition of cell growth at 50 uM after 72 hrs by MTT assay | Mus musculus | 40 | ALA3751721 | cell-based format | Scientific Literature | |
9. | ALA640131 | Binding | Association constant for binding to poly [d(A-T)] | 64 | ALA1121781 | nucleic acid format | Scientific Literature | ||
10. | ALA640132 | Binding | Association constant for binding to poly [d(G-C)] | 64 | ALA1121781 | nucleic acid format | Scientific Literature | ||
11. | ALA633895 | Physicochemical | Ionization constant (pKa) | 181 | ALA1122023 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA635165 | Physicochemical | Ionisation constant (pKa) | 61 | ALA1121781 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA656146 | Functional | Inhibitory concentration against ethidium binding to DNA | Bos taurus | 63 | ALA1121781 | assay format | Scientific Literature | |
14. | ALA703726 | Functional | Drug concentration in mole/kg/day providing 50% extension of life in intraperitoneally implanted leukemia L1210 mice. | Mus musculus | 771 | ALA1122023 | cell-based format | Scientific Literature | |
15. | ALA813896 | ADME | Compound concentration in mole/kg/day lethal to 10% of mice | Mus sp. | 771 | ALA1122023 | organism-based format | Scientific Literature | |
16. | ALA725397 | Functional | Maximum percent increase in life span of mice was determined by L1210 assay | Mus musculus | 21 | ALA1121781 | organism-based format | Scientific Literature | |
17. | ALA727536 | ADME | Drug dose that is lethal to 10% of animals was measured | Mus musculus | 63 | ALA1121781 | organism-based format | Scientific Literature |