| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1794345 | F | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 170,142 | organism-based format | PubChem BioAssays | ||
| 2. | ALA1925517 | F | Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as potentiation of EC20 glutamate-induced calcium mobilization after 2.5 mins | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA1925518 | F | Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as potentiation of EC20 glutamate-induced calcium mobilization after 2.5 mins relative to PHCCC | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA1925520 | F | Antagonist activity at human muscarinic acetylcholine receptor 4 expressed in CHO cells co-expressing Gqi5 assessed as inhibition of acetylcholine-induced calcium mobilization at 10 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1925521 | F | Antagonist activity at human muscarinic acetylcholine receptor 4 expressed in CHO cells co-expressing Gqi5 assessed as inhibition of acetylcholine-induced calcium mobilization | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1925522 | F | Antagonist activity at human muscarinic acetylcholine receptor 1 expressed in CHO cells co-expressing Gqi5 assessed as inhibition of acetylcholine-induced calcium mobilization | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA1925523 | B | Positive allosteric modulation of rat mGlu4 receptor expressed in human HEK293 cells co-expressing GIRK potassium channels assessed as potentiation of carbachol-induced thallium flux measured between 10 to 20 secs | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA1925527 | B | Positive allosteric modulation of rat mGlu4 receptor expressed in human HEK293 cells co-expressing GIRK potassium channels assessed as potentiation of glutamate-induced response at 30 uM relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA1794546 | F | PUBCHEM_BIOASSAY: Dose responses of compounds that inhibit the Choline Transporter (CHT) - 10 point CRC. (Class of assay: confirmatory) | 274 | assay format | PubChem BioAssays | |||
| 10. | ALA1794553 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] | Homo sapiens | 58,172 | cell-based format | PubChem BioAssays | ||
| 11. | ALA1794580 | F | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 130,890 | organism-based format | PubChem BioAssays | ||
| 12. | ALA1794584 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] | 63,980 | assay format | PubChem BioAssays | |||
| 13. | ALA2114807 | F | PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) | Homo sapiens | 15,516 | assay format | PubChem BioAssays | ||
| 14. | ALA2114810 | F | PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) | Homo sapiens | 86,035 | assay format | PubChem BioAssays | ||
| 15. | ALA1614236 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) | Influenza A virus (A/WSN/1933(H1N1)) | 32,268 | assay format | PubChem BioAssays | ||
| 16. | ALA1614249 | B | PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] | Equus caballus | 42,059 | single protein format | PubChem BioAssays | ||
| 17. | ALA1613808 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) | Homo sapiens | 7,224 | assay format | PubChem BioAssays | ||
| 18. | ALA1614257 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) | Homo sapiens | 37,649 | assay format | PubChem BioAssays | ||
| 19. | ALA1614414 | F | PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion. (Class of assay: confirmatory) | Saccharomyces cerevisiae | 8,343 | organism-based format | PubChem BioAssays | ||
| 20. | ALA1614544 | F | PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) | Homo sapiens | 36,150 | assay format | PubChem BioAssays |
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