# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA632991 | B | Dissociation constant (Kb) against LTD4 | Cavia porcellus | 28 | protein format | Scientific Literature | ||
2. | ALA637828 | A | Negative logarithm of the molar dissociation constant | 8 | assay format | Scientific Literature | |||
3. | ALA666490 | B | Inhibition constant for displacement of [3H]LTD4 on guinea pig lung parenchymal membranes. | Cavia porcellus | 24 | tissue-based format | Scientific Literature | ||
4. | ALA820839 | F | Effective dose of compound was measured in vivo for blocking LTD4 induced dyspnea after po administration. | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
5. | ALA4014607 | B | Displacement of [3H]LTD4 from cysteinyl leukotriene receptor 1 in Hartley guinea pig parenchymal membrane after 30 mins by liquid scintillation counting method | Cavia porcellus | 3 | assay format | Scientific Literature | ||
6. | ALA4014615 | A | Oral bioavailability in dog | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
7. | ALA4014616 | A | Oral bioavailability in rat | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
8. | ALA4256759 | B | Partial agonist activity at human PPARgamma LBD expressed HEK293T cells after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 10 | assay format | Scientific Literature | ||
9. | ALA4256760 | B | Partial agonist activity at human PPARgamma LBD expressed HEK293T cells at 1 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay relative to pioglitazone | Homo sapiens | 10 | assay format | Scientific Literature | ||
10. | ALA4256761 | B | Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by spectrofluorimetry | Homo sapiens | 10 | single protein format | Scientific Literature | ||
11. | ALA4256762 | F | Antagonist potency at human CysLT1R expressed in African green monkey COS7 cells assessed as inhibition of LTD4-induced Ca2+ levels after 60 mins by fura-2/AM-fluorescence based spectrofluorimetry | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
12. | ALA4263658 | B | Inhibition of West Nile virus NS2B-NS3 protease at 60 uM using Mca-KKR-GDap(DNP)AK-NH2 as substrate measured every 30 secs for 20 mins by FRET assay | West Nile virus | 13 | assay format | Scientific Literature |