# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA640722 | A | Tested for Half- life in 10% rat plasma homogenate at 37 degree centigrade; Not detected at 60 min after incubation | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
2. | ALA640723 | A | Tested for Half- life in 2% rat liver homogenate; Not detected at 60 min after incubation | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
3. | ALA639536 | A | Tested for half- life in 1% rat small intestine homogenate; Not detected at 60 min after incubation | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
4. | ALA639996 | A | Bioavailability determined from the ratio of AUC(plasma) for 0 to infinity after oral dosing of the test compound (10 mg/kg) to intravenous administration of CD-11194 (1 mg/kg) in rats | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
5. | ALA646983 | B | Inhibition of specific binding of [125I]angiotensin II (0.2 nM) to angiotensin II receptor in bovine adrenal cortex | Bos taurus | 34 | tissue-based format | Scientific Literature | ||
6. | ALA646985 | B | In vitro for inhibition of specific binding of [125I]-angiotensin II (0.02 nM) to bovine adrenal cortex | Bos taurus | 35 | tissue-based format | Scientific Literature | ||
7. | ALA878959 | F | Percent inhibition of angiotensin II (0.1 ug/kg iv) -induced pressor response 3h after administration of test compounds (1 mg/kg po) in conscious male Sprague-Dawley rats | 33 | organism-based format | Scientific Literature | |||
8. | ALA783565 | F | Percent inhibition of angiotensin II (0.1 ug/kg iv) -induced pressor response 7 hr after administration of test compounds (1 mg/kg po) in conscious male Sprague-Dawley rats | 24 | organism-based format | Scientific Literature | |||
9. | ALA788037 | F | Inhibitory activity on AII (100 ng/kg iv) -induced pressor response after administration at 0.1 mg/kg po in Dawley rats at 0.5 h | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
10. | ALA788038 | F | Inhibitory activity on AII (100 ng/kg iv) -induced pressor response after administration at 0.1 mg/kg po in Dawley rats at 1 h | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
11. | ALA788039 | F | Inhibitory activity on AII (100 ng/kg iv)-induced pressor response after administration at 0.1 mg/kg po in conscious male Sprague-Dawley rats at 2 h. | 39 | organism-based format | Scientific Literature | |||
12. | ALA788040 | F | Inhibitory activity on AII (100 ng/kg iv)-induced pressor response after administration at 0.1 mg/kg po in conscious male Sprague-Dawley rats at 24 h. | 37 | organism-based format | Scientific Literature | |||
13. | ALA788041 | F | Inhibitory activity on AII (100 ng/kg iv)-induced pressor response after administration at 0.1 mg/kg po in conscious male Sprague-Dawley rats at 3 h. | 39 | organism-based format | Scientific Literature | |||
14. | ALA786468 | F | Inhibitory activity on AII (100 ng/kg iv)-induced pressor response after administration at 0.1 mg/kg po in conscious male Sprague-Dawley rats at 5 h. | 39 | organism-based format | Scientific Literature | |||
15. | ALA786469 | F | Inhibitory activity on AII (100 ng/kg iv)-induced pressor response after administration at 0.1 mg/kg po in conscious male Sprague-Dawley rats at 7 h. | 39 | organism-based format | Scientific Literature | |||
16. | ALA797277 | F | In vivo inhibition of angiotensin II (0.1 ug/kg) induced increase in blood pressure in conscious male rat at 3 mg/kg for 3h/7h. | 21 | organism-based format | Scientific Literature | |||
17. | ALA3056264 | B | Displacement of [125I]angiotensin 2 from type-1 angiotensin 2 receptor in Bos taurus (bovine) adrenal cortical membrane | Bos taurus | 33 | assay format | Scientific Literature |