# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA633908 | A | Oral bioavailability in rat | Rattus norvegicus | 4 | ALA1134619 | organism-based format | Scientific Literature | |
2. | ALA644252 | A | Plasma clearance in rats was determined | Rattus norvegicus | 4 | ALA1134619 | organism-based format | Scientific Literature | |
3. | ALA874418 | A | Volume distribution at steady state in rats was determined | Rattus norvegicus | 4 | ALA1134619 | organism-based format | Scientific Literature | |
4. | ALA642319 | A | Half life period in rats was determined | Rattus norvegicus | 4 | ALA1134619 | organism-based format | Scientific Literature | |
5. | ALA746894 | F | Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activity | 24 | ALA1134619 | cell-based format | Scientific Literature | ||
6. | ALA872728 | F | Compound is screened in AP1 cells expressing human NHE-2 for sodium hydrogen exchange activity | 3 | ALA1134619 | cell-based format | Scientific Literature | ||
7. | ALA748618 | F | Compound is screened in AP1 cells expressing human NHE-3 for sodium hydrogen exchange activity | 3 | ALA1134619 | cell-based format | Scientific Literature | ||
8. | ALA748619 | F | Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activity | 3 | ALA1134619 | cell-based format | Scientific Literature | ||
9. | ALA873248 | F | Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | 21 | ALA1146688 | cell-based format | Scientific Literature | ||
10. | ALA3881449 | B | Inhibition of full length human C-terminal HA-tagged human NHE5 expressed in chinese hamster AP1 cells assessed as inhibition of acid-induced 22NA+ influx by liquid scintillation spectroscopy | Homo sapiens | 6 | ALA3880442 | cell-based format | Patent Bioactivity Data | |
11. | ALA3881456 | B | Inhibition of human NHE1 expressed in CHO-K1 cells assessed as inhibition of Na+/Ca+ exchange activity measured after 5 mins by BACEF-AM dye based fluorescence analysis | Homo sapiens | 1 | ALA3880442 | cell-based format | Patent Bioactivity Data | |
12. | ALA3881457 | B | Inhibition of human NHE2 expressed in CHO-K1 cells assessed as inhibition of Na+/Ca+ exchange activity measured after 5 mins by BACEF-AM dye based fluorescence analysis | Homo sapiens | 1 | ALA3880442 | cell-based format | Patent Bioactivity Data | |
13. | ALA3881458 | B | Inhibition of human NHE3 expressed in CHO-K1 cells assessed as inhibition of Na+/Ca+ exchange activity measured after 5 mins by BACEF-AM dye based fluorescence analysis | Homo sapiens | 1 | ALA3880442 | cell-based format | Patent Bioactivity Data | |
14. | ALA3882215 | B | Inhibition of NHE-1 (unknown origin) | Homo sapiens | 8 | ALA3881530 | single protein format | Patent Bioactivity Data | |
15. | ALA3882218 | B | Inhibition of NHE-2 (unknown origin) | Homo sapiens | 7 | ALA3881530 | single protein format | Patent Bioactivity Data | |
16. | ALA3882220 | B | Inhibition of NHE-5 (unknown origin) | Homo sapiens | 6 | ALA3881530 | single protein format | Patent Bioactivity Data | |
17. | ALA3882221 | B | Inhibition of NHE-3 (unknown origin) | Homo sapiens | 7 | ALA3881530 | single protein format | Patent Bioactivity Data | |
18. | ALA4037096 | B | Inhibition of human NHE1 by cell based assay | Homo sapiens | 2 | ALA4033775 | cell-based format | Scientific Literature | |
19. | ALA4037110 | A | Clearance in po dosed rat | Rattus norvegicus | 2 | ALA4033775 | organism-based format | Scientific Literature | |
20. | ALA4037111 | A | Half life in po dosed rat | Rattus norvegicus | 2 | ALA4033775 | organism-based format | Scientific Literature |