| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1614421 | B | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | Homo sapiens | 49,165 | ALA1201862 | single protein format | PubChem BioAssays | |
| 2. | ALA1614502 | F | PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | 23,781 | ALA1201862 | assay format | PubChem BioAssays | ||
| 3. | ALA1738312 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] | Homo sapiens | 55,525 | ALA1201862 | assay format | PubChem BioAssays | |
| 4. | ALA1738637 | F | PUBCHEM_BIOASSAY: IN Cell qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2660, AID2666, AID2667, AID2668, AID2681, AID493208] | Homo sapiens | 1,307 | ALA1201862 | assay format | PubChem BioAssays | |
| 5. | ALA1737991 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] | Homo sapiens | 51,376 | ALA1201862 | assay format | PubChem BioAssays | |
| 6. | ALA1738442 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] | Homo sapiens | 90,358 | ALA1201862 | assay format | PubChem BioAssays | |
| 7. | ALA1738694 | F | PUBCHEM_BIOASSAY: Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2660, AID2666, AID2667, AID2668, AID2681, AID504465] | Homo sapiens | 2,694 | ALA1201862 | assay format | PubChem BioAssays | |
| 8. | ALA1777498 | B | Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-dUTP incorporation into DNA strand by rapid plate assay | Vaccinia virus | 28 | ALA1773050 | single protein format | Scientific Literature | |
| 9. | ALA1777499 | A | Cytotoxicity against african green monkey BSC1 cells infected with Vaccinia virus assessed as lactate dehydrogenase release after 20 hrs by microplate reader | Chlorocebus aethiops | 28 | ALA1773050 | cell-based format | Scientific Literature | |
| 10. | ALA1777500 | B | Binding affinity at Vaccinia virus WR strain D4 assessed as change in unfolding transition temperature at 50 uM by thermofluor method | Vaccinia virus WR | 27 | ALA1773050 | single protein format | Scientific Literature | |
| 11. | ALA1777502 | F | Antiviral activity against Vaccinia virus infected in BSC-1 cells by plaque reduction assay | Vaccinia virus | 28 | ALA1773050 | organism-based format | Scientific Literature | |
| 12. | ALA1777504 | B | Binding affinity at Vaccinia virus WR strain D4 assessed as melting temperature at 50 uM by thermofluor method (Rvb = 38.4 +/- 1.6 degC) | Vaccinia virus WR | 27 | ALA1773050 | single protein format | Scientific Literature | |
| 13. | ALA1794375 | B | PUBCHEM_BIOASSAY: qHTS for inhibitors of binding or entry into cells for Marburg Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249, AID540278] | 83,389 | ALA1201862 | assay format | PubChem BioAssays | ||
| 14. | ALA1794553 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] | Homo sapiens | 58,172 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 15. | ALA2114713 | F | PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) | Bacillus subtilis | 20,646 | ALA1201862 | assay format | PubChem BioAssays | |
| 16. | ALA2114747 | F | PubChem BioAssay. InCell qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in WT MEF Cells: Hit Validation. (Class of assay: confirmatory) | Homo sapiens | 280 | ALA1201862 | assay format | PubChem BioAssays | |
| 17. | ALA2114908 | F | PubChem BioAssay. qHTS of Nrf2 Activators. (Class of assay: confirmatory) | Homo sapiens | 9,197 | ALA1201862 | assay format | PubChem BioAssays | |
| 18. | ALA2354221 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT. (Class of assay: confirmatory) | 172,532 | ALA1201862 | assay format | PubChem BioAssays | ||
| 19. | ALA2354254 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT. (Class of assay: confirmatory) | 153,867 | ALA1201862 | assay format | PubChem BioAssays |
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