# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA751882 | Binding | Activity against rat cortical and hippocampal membrane strychnine-insensitive N-methyl-D-aspartate glutamate receptor 1 using [3H]-gly | Rattus norvegicus | 11 | ALA1124998 | tissue-based format | Scientific Literature | |
2. | ALA752489 | Binding | Ability to compete with [3H]glycine for strychnine-insensitive binding sites on rat cortical and hippocampal membrane | 28 | ALA1126038 | tissue-based format | Scientific Literature | ||
3. | ALA747014 | Binding | Selectivity ratio for CPP and gly NMDA binding | Rattus norvegicus | 11 | ALA1124998 | protein complex format | Scientific Literature | |
4. | ALA747511 | Binding | Activity against rat cortical and hippocampal membrane N-methyl-D-aspartate glutamate receptor 1/2A/2B/2C/2D using [3H]CPP | Rattus norvegicus | 11 | ALA1124998 | tissue-based format | Scientific Literature | |
5. | ALA749385 | Binding | Ability to compete with [3H]CCP for rat cortical and hippocampal membrane glutamate binding site. | 17 | ALA1126038 | tissue-based format | Scientific Literature | ||
6. | ALA849492 | Binding | Ratio of the inhibitory activity against [3H]-CCP for rat cortical and hippocampal membrane glutamate binding site to [3H]glycine for rat cortical and hippocampal membrane binding site. | 16 | ALA1126038 | tissue-based format | Scientific Literature | ||
7. | ALA1952453 | Binding | Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysis | Homo sapiens | 12 | ALA1949584 | single protein format | Scientific Literature | |
8. | ALA1952454 | Binding | Ratio of compound IC50 to indole-3-propionic acid IC50 for human recombinant KAT1 | Homo sapiens | 3 | ALA1949584 | single protein format | Scientific Literature | |
9. | ALA4200085 | Functional | Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization after 1 hr by Oregon Green BAPTA-1/AM dye-based fluorescence assay | Homo sapiens | 51 | ALA4196130 | cell-based format | Scientific Literature | |
10. | ALA4200090 | Functional | Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of calcium mobilization at >30 uM after 1 hr by Oregon Green BAPTA-1/AM dye-based fluorescence assay relative to control | Homo sapiens | 17 | ALA4196130 | cell-based format | Scientific Literature | |
11. | ALA4200092 | Binding | Displacement of [3H]glycine from NMDA receptor in rat cortical and hippocampal membranes | Rattus norvegicus | 7 | ALA4196130 | assay format | Scientific Literature | |
12. | ALA4200093 | Binding | Displacement of [3H]CCP from NMDA receptor glutamate binding site in rat cortical and hippocampal membranes | Rattus norvegicus | 5 | ALA4196130 | assay format | Scientific Literature |