# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA621158 | F | Irreversible inhibition of ATP binding site of EGFR (lack of phosphorylated EGFR) in A431 cells 8 hour after washing cells free of the inhibitor) | 17 | ALA1132213 | cell-based format | Scientific Literature | ||
2. | ALA674017 | B | Inhibition of EGF-stimulated autophosphorylation of epidermal growth factor receptor (EGFR) in A431 cells | Homo sapiens | 13 | ALA1132213 | cell-based format | Scientific Literature | |
3. | ALA674018 | B | Inhibition of phosphorylation of glutamic acid/tyrosine random copolymer by isolated epidermal growth factor receptor (EGFR) | 13 | ALA1132213 | single protein format | Scientific Literature | ||
4. | ALA673949 | B | Inhibition of heregulin-stimulated autophosphorylation of ERBB2 receptor kinase in MDA-MB-453 cells. | Homo sapiens | 12 | ALA1132213 | cell-based format | Scientific Literature | |
5. | ALA726266 | F | In vivo activity against A431 xenograft in nude mice, net reduction in tumor burden at 200 mg/kg peroral dose | 2 | ALA1132213 | organism-based format | Scientific Literature | ||
6. | ALA726269 | F | In vivo activity against H125 xenograft in nude mice, net reduction in tumor burden at 200 mg/kg dose | 3 | ALA1132213 | organism-based format | Scientific Literature | ||
7. | ALA724282 | F | In vivo activity against A431 xenograft in nude mice, ratio of treated/control median tumor mass at 200 mg/kg peroral dose | 2 | ALA1132213 | organism-based format | Scientific Literature | ||
8. | ALA724286 | F | In vivo activity against H125 xenograft in nude mice, ratio of treated/control median tumor mass at 200 mg/kg peroral dose | 4 | ALA1132213 | organism-based format | Scientific Literature | ||
9. | ALA727318 | F | Difference in days for treated (T) and control (C) tumors to reach 750 mg at 200 mg/kg ip dose | Mus musculus | 3 | ALA1132213 | organism-based format | Scientific Literature | |
10. | ALA730858 | F | In vivo activity against A431 xenograft in nude mice, weight change at 200 mg/kg peroral dose | 1 | ALA1132213 | organism-based format | Scientific Literature | ||
11. | ALA730862 | F | In vivo activity against H125 xenograft in nude mice, weight change at 200 mg/kg peroral dose | 3 | ALA1132213 | organism-based format | Scientific Literature |