# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA619174 | B | Percent inhibition of radioligand [3H]-LSD binding to 5-HT receptor at 10 uM concentration | Mus musculus | 1 | ALA1127300 | assay format | Scientific Literature | |
2. | ALA631366 | P | LogD value of the compound | 4 | ALA1128339 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA644329 | B | Percent inhibition of radioligand [3H]NECA binding to A1,A2 receptor at 10 uM concentration | 1 | ALA1127300 | assay format | Scientific Literature | ||
4. | ALA643606 | B | Percent inhibition of radioligand [3H]prazosin binding to alpha-1 receptor at 10 uM concentration | 1 | ALA1127300 | protein format | Scientific Literature | ||
5. | ALA646772 | B | Percent inhibition of radioligand [3H]rauwolscine binding to alpha-2 receptor at 10 uM concentration | 1 | ALA1127300 | protein format | Scientific Literature | ||
6. | ALA655085 | B | Percent inhibition of radioligand [3H]DHAP binding to beta receptor at 10 uM concentration | Mus musculus | 1 | ALA1127300 | protein format | Scientific Literature | |
7. | ALA650544 | B | Percent inhibition of [3H]flunarazine binding to GABA-A benzodiazepine receptor at 10 uM | 1 | ALA1127300 | assay format | Scientific Literature | ||
8. | ALA655291 | B | Percent inhibition of [3H]nitrendipine binding to [Ca2+] channel at 10 uM | Mus musculus | 1 | ALA1127300 | assay format | Scientific Literature | |
9. | ALA672775 | B | Percent inhibition of radioligand [3H]raclopride binding to D2 receptor at 10 uM concentration | Mus musculus | 1 | ALA1127300 | single protein format | Scientific Literature | |
10. | ALA673333 | B | Percent inhibition of radioligand [3H]SCH-23,390 binding to dopamine receptor D1 at 10 uM concentration | 1 | ALA1127300 | single protein format | Scientific Literature | ||
11. | ALA673335 | B | Percent inhibition of radioligand [3H]SCH-23390 binding to dopamine receptor D1 at 10 uM concentration | Mus musculus | 1 | ALA1127300 | single protein format | Scientific Literature | |
12. | ALA692994 | B | Percent inhibition of radioligand [3H]pyrilamine binding to H1 receptor at 10 uM concentration | 1 | ALA1127300 | single protein format | Scientific Literature | ||
13. | ALA737773 | F | Electrophysiological responses in closed channel block to NMDA were recorded in 13-day old mouse cortical neuronal cultures. | Mus musculus | 2 | ALA1127300 | organism-based format | Scientific Literature | |
14. | ALA737774 | F | Electrophysiological responses in open channel block to NMDA were recorded in 13-day old mouse cortical neuronal cultures. | Mus musculus | 2 | ALA1127300 | organism-based format | Scientific Literature | |
15. | ALA740156 | F | In vitro neuroprotective efficacy determined to protect cultured mouse cortical neurons from an excitotoxic exposure to NMDA | Mus musculus | 9 | ALA1127300 | organism-based format | Scientific Literature | |
16. | ALA743372 | F | Neuroprotection was determined against NMDA induced cell death in cultured mouse cortical neuron. | Mus musculus | 8 | ALA1128370 | assay format | Scientific Literature | |
17. | ALA743374 | F | NMDA antagonistic activity was evaluated in vivo in cultured mouse cortical neurons by patch clamp recordings designed to measure closed state binding to NMDA receptor-ionophore complex | Mus musculus | 4 | ALA1128339 | organism-based format | Scientific Literature | |
18. | ALA743375 | F | NMDA antagonistic activity was evaluated in vivo in cultured mouse cortical neurons by patch clamp recordings designed to measure open state binding to NMDA receptor-ionophore complex | Mus musculus | 4 | ALA1128339 | organism-based format | Scientific Literature | |
19. | ALA743376 | F | NMDA antagonistic activity was evaluated in vivo in cultured mouse cortical neurons by patch clamp recordings designed to measure closed state binding to NMDA receptor-ionophore complex at 100 uM | Mus musculus | 2 | ALA1128339 | organism-based format | Scientific Literature | |
20. | ALA743377 | F | Ratio of IC50 value for closed channel binding to that of open channel binding. | Mus musculus | 3 | ALA1128339 | organism-based format | Scientific Literature |