# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA628525 | ADME | The efflux rate constant of the compound | 6 | ALA1122176 | assay format | Scientific Literature | ||
2. | ALA639174 | ADME | Influx velocity of the compound | 6 | ALA1122176 | assay format | Scientific Literature | ||
3. | ALA655016 | Functional | Relative activity when compared to the activity of aminopterin in CCRF-CEM Human leukemia cell at a concentration of 50 uM | Homo sapiens | 4 | ALA1125907 | cell-based format | Scientific Literature | |
4. | ALA665161 | Functional | Concentration required to inhibit the growth of chang liver cells | Homo sapiens | 6 | ALA1129929 | assay format | Scientific Literature | |
5. | ALA668094 | Binding | Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase. | 8 | ALA1125907 | single protein format | Scientific Literature | ||
6. | ALA667313 | Binding | Binding affinity towards Dihydrofolate reductase derived from L1210 cells using [3H]- MTX as the radioligand | 4 | ALA1124936 | cell-based format | Scientific Literature | ||
7. | ALA667321 | Binding | Concentration inhibiting dihydrofolate reductase derived from L1210 cells | 4 | ALA1124936 | cell-based format | Scientific Literature | ||
8. | ALA667324 | Binding | Inhibition of Dihydrofolate reductase (DHFR) enzyme derived from L1210 cells expressed as Ki (pM) | 7 | ALA1126936 | cell-based format | Scientific Literature | ||
9. | ALA667329 | Binding | Tested for inhibition of dihydrofolate reductase enzyme | 5 | ALA1122176 | single protein format | Scientific Literature | ||
10. | ALA664703 | Binding | Concentration required to inhibit Lactobacillus casei derived Dihydrofolate reductase activity by 50% | Lacticaseibacillus casei | 7 | ALA1121695 | single protein format | Scientific Literature | |
11. | ALA668391 | Functional | Concentration required for the 50% growth inhibition of Lactobacillus casei dihydrofolate reductase enzyme | Lacticaseibacillus casei | 1 | ALA1122176 | assay format | Scientific Literature | |
12. | ALA663892 | Functional | Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 2) | Lacticaseibacillus casei | 3 | ALA1123948 | assay format | Scientific Literature | |
13. | ALA663893 | Functional | Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 3) | Lacticaseibacillus casei | 3 | ALA1123948 | assay format | Scientific Literature | |
14. | ALA663894 | Functional | Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 4) | Lacticaseibacillus casei | 3 | ALA1123948 | assay format | Scientific Literature | |
15. | ALA663895 | Functional | Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 5) | Lacticaseibacillus casei | 3 | ALA1123948 | assay format | Scientific Literature | |
16. | ALA663896 | Functional | Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 6) | Lacticaseibacillus casei | 2 | ALA1123948 | assay format | Scientific Literature | |
17. | ALA706141 | Functional | % increase in lifespan was measured at 15 mg/kg dosage after ip administration | Mus musculus | 5 | ALA1122176 | organism-based format | Scientific Literature | |
18. | ALA706142 | Functional | % increase in lifespan was measured at 3 mg/kg dosage after ip administration | Mus musculus | 5 | ALA1122176 | organism-based format | Scientific Literature | |
19. | ALA704903 | Functional | Concentration inhibiting L1210 cell growth in culture | Mus musculus | 5 | ALA1124936 | cell-based format | Scientific Literature | |
20. | ALA704272 | Functional | Minimum inhibitory concentration of compound was tested for growth inhibition of L1210 cells | Mus musculus | 5 | ALA1122176 | cell-based format | Scientific Literature |