# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615124 | F | In vitro cell cytotoxicity was determined against 143B cell line | Homo sapiens | 14 | ALA1149129 | cell-based format | Scientific Literature | |
2. | ALA615128 | F | In vitro cell cytotoxicity was determined against 143B-LTK cell line | Homo sapiens | 14 | ALA1149129 | cell-based format | Scientific Literature | |
3. | ALA675103 | F | In vitro cell cytotoxicity was determined against EMT-6 cell line | Mus musculus | 13 | ALA1149129 | cell-based format | Scientific Literature | |
4. | ALA699465 | F | In vitro cell cytotoxicity was determined against Hs 578.Bst cell line | Homo sapiens | 11 | ALA1149129 | cell-based format | Scientific Literature | |
5. | ALA701383 | F | In vitro cell cytotoxicity was determined against KBALB cell line | Mus musculus | 15 | ALA1149129 | cell-based format | Scientific Literature | |
6. | ALA701386 | F | In vitro cell cytotoxicity was determined against KBALB-STK cell line | Mus musculus | 15 | ALA1149129 | cell-based format | Scientific Literature | |
7. | ALA842729 | F | In vitro percent nitric oxide released from the test compound was determined as the percent of nitrite (NO2-) produced in phosphate buffered saline at 16 hr | 12 | ALA1149129 | assay format | Scientific Literature | ||
8. | ALA845201 | F | In vitro percent nitric oxide released from the test compound was determined as the percent of nitrite (NO2-) produced in phosphate buffered saline at 1 hr | 12 | ALA1149129 | assay format | Scientific Literature | ||
9. | ALA845560 | F | In vitro percent nitric oxide released from the test compound was determined as the percent of nitrite (NO2-) produced in the present of L-cysteine in Phosphate buffer saline at 16 hr | 12 | ALA1149129 | assay format | Scientific Literature | ||
10. | ALA845561 | F | In vitro percent nitric oxide released from the test compound was determined as the percent of nitrite (NO2-) produced in the present of L-cysteine in Phosphate buffer saline at 1 hr | 12 | ALA1149129 | assay format | Scientific Literature | ||
11. | ALA978115 | F | Antitrypanosomal activity against Trypanosoma cruzi Tulahuen 2 assessed as inhibition of epimastigotes growth after 5 days by MTT assay relative to control | Trypanosoma cruzi | 40 | ALA1140032 | organism-based format | Scientific Literature | |
12. | ALA1219905 | B | Inhibition of MDR1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assay | 35 | ALA1212912 | cell-based format | Scientific Literature | ||
13. | ALA1219907 | B | Induction of MRP1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assay | 11 | ALA1212912 | cell-based format | Scientific Literature | ||
14. | ALA1641185 | B | Selectivity for Trypanosoma cruzi triosephosphate isomerase over human triosephosphate isomerase | 226 | ALA1629474 | assay format | Scientific Literature | ||
15. | ALA1641187 | F | Antiparasitic activity against Trypanosoma cruzi T2 epimastigotes assessed as growth inhibition at 25 uM after 5 days | Trypanosoma cruzi | 227 | ALA1629474 | organism-based format | Scientific Literature | |
16. | ALA1641189 | B | Inhibition of Trypanosoma cruzi triosephosphate isomerase at 100 uM after 2 hrs | Trypanosoma cruzi | 227 | ALA1629474 | single protein format | Scientific Literature | |
17. | ALA1641190 | B | Inhibition of Trypanosoma cruzi triosephosphate isomerase at 400 uM after 2 hrs | Trypanosoma cruzi | 227 | ALA1629474 | single protein format | Scientific Literature | |
18. | ALA1959228 | B | Inhibition of TNF-alpha-induced NFkappaB activation expressed in human HT-29 cells coexpressing hrGFP at 20 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis relative to control | Homo sapiens | 1 | ALA1955718 | cell-based format | Scientific Literature | |
19. | ALA1959229 | A | Cytotoxicity against human HT-29 cells expressing NF-kappaB-hrGFP assessed as highest non-cytotoxic dose for 100% cell survival after 24 hrs by MTT assay | Homo sapiens | 36 | ALA1955718 | cell-based format | Scientific Literature | |
20. | ALA1959656 | B | Inhibition of NF-kappaB activation expressed in human HT-29 cells assessed as inhibition of TNFalpha-stimulated IL8 release at 20 uM after 24 hrs by flow cytometric analysis relative to control | Homo sapiens | 1 | ALA1955718 | cell-based format | Scientific Literature |