# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA619657 | F | Increase in phosphoinositide (PI) metabolism in A9L-m1 cells at 100 uM. | Mus musculus | 20 | ALA1125621 | cell-based format | Scientific Literature | |
2. | ALA619660 | F | Increase in phosphoinositide (PI) metabolism in A9L-cholinergic receptor, muscarinic 3 expressing cells was measured at 100 uMolar | 28 | ALA1125621 | assay format | Scientific Literature | ||
3. | ALA663185 | F | The percent inhibition of cyclic AMP(cAMP) formation in NG108-15 cells at 100 uM. | Mus musculus | 16 | ALA1125621 | cell-based format | Scientific Literature | |
4. | ALA684549 | F | Concentration that elicits 50% of its own maximum contractile response, in guinea pig ileum | Cavia porcellus | 11 | ALA1124056 | organism-based format | Scientific Literature | |
5. | ALA688026 | F | Efficacy relative to that of carbachol, measured in guinea pig ileum | Cavia porcellus | 11 | ALA1124056 | organism-based format | Scientific Literature | |
6. | ALA686995 | F | Equilibrium dissociation constant muscarinic receptor complex, measured in guinea pig ileum | Cavia porcellus | 24 | ALA1124056 | tissue-based format | Scientific Literature | |
7. | ALA692167 | F | Maximum contractile response relative to that elicited by carbachol, in guinea pig ileum | Cavia porcellus | 17 | ALA1124056 | organism-based format | Scientific Literature | |
8. | ALA717795 | F | ED50 value as cholinergic agonism by measuring lacrimation in mice (in vivo) | Mus musculus | 65 | ALA1125599 | organism-based format | Scientific Literature | |
9. | ALA717945 | F | ED50 value as cholinergic agonist by measuring salivation in mice (in vivo) | Mus musculus | 65 | ALA1125599 | organism-based format | Scientific Literature | |
10. | ALA717946 | F | ED50 value as cholinergic agonist by measuring tremors in mice (in vivo) | Mus musculus | 65 | ALA1125599 | organism-based format | Scientific Literature | |
11. | ALA717947 | F | ED50 value determined as oxotremorine antagonism by measuring lacrimation in mice (in vivo) | Mus musculus | 64 | ALA1125599 | organism-based format | Scientific Literature | |
12. | ALA716184 | F | ED50 value determined as oxotremorine antagonism by measuring salivation in mice (in vivo) | Mus musculus | 64 | ALA1125599 | organism-based format | Scientific Literature | |
13. | ALA716185 | F | ED50 value determined as oxotremorine antagonism by measuring tremors in mice (in vivo) | Mus musculus | 64 | ALA1125599 | organism-based format | Scientific Literature | |
14. | ALA748432 | B | Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptor | Rattus norvegicus | 12 | ALA1126443 | protein format | Scientific Literature | |
15. | ALA748213 | B | Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptor | Rattus norvegicus | 12 | ALA1126443 | protein format | Scientific Literature | |
16. | ALA745522 | B | Percent increase in [3H]myo-inositol at muscarinic acetylcholine receptor M3 from SK-N-SH human neuroblastoma cells | 39 | ALA1124832 | cell-based format | Scientific Literature | ||
17. | ALA744388 | B | Percent binding affinity at muscarinic acetylcholine receptor M3 from SK-N-SH human neuroblastoma cells in presence of [3H]NMS | 39 | ALA1124832 | cell-based format | Scientific Literature | ||
18. | ALA749269 | B | Binding affinity was determined using [3H]-NMS for Muscarinic acetylcholine receptor in SK-N-SH neuroblastoma cells | Homo sapiens | 6 | ALA1124832 | cell-based format | Scientific Literature | |
19. | ALA749278 | B | Displacement of [3H]N-methylscopolamine ([3H]NMS) binding at muscarinic acetylcholine receptor in rat cerebral cortical membranes | 27 | ALA1125621 | cell membrane format | Scientific Literature | ||
20. | ALA748794 | B | Evaluated for displacement of [3H]oxotremorine-M binding ([3H]OXO-M) at muscarinic acetylcholine receptor in rat forebrain membranes | 25 | ALA1125621 | cell membrane format | Scientific Literature |