# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA676676 | Functional | In vitro growth inhibition against Entamoeba histolytica | Entamoeba histolytica | 102 | ALA1148279 | organism-based format | Scientific Literature | |
2. | ALA681824 | Functional | Inhibitory activity, for stimulation of TNF-alpha release in gamma-delta T cells, using a constrained maximum TNF-alpha release of 2700 pg/mL | Homo sapiens | 61 | ALA1148380 | cell-based format | Scientific Literature | |
3. | ALA681825 | Functional | Inhibitory activity, for stimulation of TNF-alpha release in gamma-delta T cells, using individual observed maximum TNF-alpha release | Homo sapiens | 45 | ALA1148380 | cell-based format | Scientific Literature | |
4. | ALA681826 | Functional | pIC50 value for stimulation of TNF-alpha release in gamma-delta T cells, using a constrained maximum TNF-alpha release of 2700 pg/mL | Homo sapiens | 61 | ALA1148380 | cell-based format | Scientific Literature | |
5. | ALA681827 | Functional | pIC50 value for stimulation of TNF-alpha release in gamma-delta T cells, using individual observed maximum TNF-alpha release | Homo sapiens | 45 | ALA1148380 | cell-based format | Scientific Literature | |
6. | ALA681890 | Binding | Inhibitory activity against farnesyl Pyrophosphate Synthase was determined | Leishmania major | 61 | ALA1145906 | single protein format | Scientific Literature | |
7. | ALA681891 | Binding | Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligand | Leishmania major | 62 | ALA1145906 | single protein format | Scientific Literature | |
8. | ALA857167 | Binding | Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME? (M) | Leishmania major | 61 | ALA1145906 | single protein format | Scientific Literature | |
9. | ALA681671 | Binding | Inhibitory activity against the human recombinant geranylgeranyl diphosphate synthase (GGPPSase). | 29 | ALA1135417 | single protein format | Scientific Literature | ||
10. | ALA699877 | ADME | 50% lethal dose for inhibition of KB cells growth | Homo sapiens | 27 | ALA1135583 | cell-based format | Scientific Literature | |
11. | ALA706171 | Functional | Inhibition of L. donovani (Amastigotes) strain MHOM/ET/67/L82 maintained in pathogen free spleen from female golden hamsters | Leishmania donovani | 1 | ALA1134372 | organism-based format | Scientific Literature | |
12. | ALA700364 | Toxicity | Toxicity evaluated against human nasopharyngeal carcinoma KB cell line | Homo sapiens | 102 | ALA1148279 | cell-based format | Scientific Literature | |
13. | ALA850290 | ADME | Therapeutic index measured as the ratio of LD50 (KB cells) to IC50 (T.b. rhodesiense) | Trypanosoma brucei rhodesiense | 27 | ALA1135583 | cell-based format | Scientific Literature | |
14. | ALA910461 | Functional | Antibacterial activity against Escherichia coli W3110 | Escherichia coli | 117 | ALA1138862 | organism-based format | Scientific Literature | |
15. | ALA1217000 | Functional | Antimicrobial activity against Plasmodium falciparum | Plasmodium falciparum | 630 | ALA1212812 | organism-based format | Scientific Literature | |
16. | ALA1217007 | Functional | Antimicrobial activity against Entamoeba histolytica | Entamoeba histolytica | 304 | ALA1212812 | organism-based format | Scientific Literature | |
17. | ALA769481 | Functional | In vitro growth inhibition against Plasmodium falciparum | Plasmodium falciparum | 102 | ALA1148279 | organism-based format | Scientific Literature | |
18. | ALA817404 | Functional | In vitro growth inhibition of bloodstream-form Trypanosoma brucei rhodesiense Trypomastigotes | Trypanosoma brucei rhodesiense | 27 | ALA1135583 | organism-based format | Scientific Literature | |
19. | ALA873468 | Functional | Predicted pIC50 against Trypomastigotes Brucei rhodesiense. | Trypanosoma brucei rhodesiense | 21 | ALA1135583 | organism-based format | Scientific Literature | |
20. | ALA808707 | Functional | Inhibition of Trypanosoma rhodesiense (strain STIB900) was determined using blood stream from trypomastigotes | Trypanosoma brucei | 19 | ALA1134372 | organism-based format | Scientific Literature |