# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA676676 | Functional | In vitro growth inhibition against Entamoeba histolytica | Entamoeba histolytica | 102 | ALA1148279 | organism-based format | Scientific Literature | |
2. | ALA681824 | Functional | Inhibitory activity, for stimulation of TNF-alpha release in gamma-delta T cells, using a constrained maximum TNF-alpha release of 2700 pg/mL | Homo sapiens | 61 | ALA1148380 | cell-based format | Scientific Literature | |
3. | ALA681825 | Functional | Inhibitory activity, for stimulation of TNF-alpha release in gamma-delta T cells, using individual observed maximum TNF-alpha release | Homo sapiens | 45 | ALA1148380 | cell-based format | Scientific Literature | |
4. | ALA681826 | Functional | pIC50 value for stimulation of TNF-alpha release in gamma-delta T cells, using a constrained maximum TNF-alpha release of 2700 pg/mL | Homo sapiens | 61 | ALA1148380 | cell-based format | Scientific Literature | |
5. | ALA681827 | Functional | pIC50 value for stimulation of TNF-alpha release in gamma-delta T cells, using individual observed maximum TNF-alpha release | Homo sapiens | 45 | ALA1148380 | cell-based format | Scientific Literature | |
6. | ALA679572 | Binding | Inhibitory activity against Leishmania major Farnesyl diphosphate synthase | Leishmania major | 43 | ALA1148279 | single protein format | Scientific Literature | |
7. | ALA681892 | Binding | Inhibitory concentration against Trypanosoma brucei farnesyl pyrophosphate synthase activity | Trypanosoma brucei | 4 | ALA1136233 | single protein format | Scientific Literature | |
8. | ALA681894 | Binding | Inhibition of Trypanosoma cruzi farnesyl pyrophosphate synthase | Trypanosoma cruzi | 12 | ALA1136233 | single protein format | Scientific Literature | |
9. | ALA681895 | Binding | Binding affinity towards Trypanosoma cruzi farnesyl pyrophosphate synthase (TcFPPS) | Trypanosoma cruzi | 9 | ALA1136233 | single protein format | Scientific Literature | |
10. | ALA681671 | Binding | Inhibitory activity against the human recombinant geranylgeranyl diphosphate synthase (GGPPSase). | 29 | ALA1135417 | single protein format | Scientific Literature | ||
11. | ALA699877 | ADME | 50% lethal dose for inhibition of KB cells growth | Homo sapiens | 27 | ALA1135583 | cell-based format | Scientific Literature | |
12. | ALA706169 | Functional | Inhibition of L. donovani (Amastigotes) strain MHOM/ET/67/L82 maintained in female golden hamsters | Leishmania donovani | 14 | ALA1134372 | organism-based format | Scientific Literature | |
13. | ALA700364 | Toxicity | Toxicity evaluated against human nasopharyngeal carcinoma KB cell line | Homo sapiens | 102 | ALA1148279 | cell-based format | Scientific Literature | |
14. | ALA850290 | ADME | Therapeutic index measured as the ratio of LD50 (KB cells) to IC50 (T.b. rhodesiense) | Trypanosoma brucei rhodesiense | 27 | ALA1135583 | cell-based format | Scientific Literature | |
15. | ALA851069 | ADME | Therapeutic index was expressed as ratio of LD50 for KB cell line to IC50 against Entamoeba histolytica | 47 | ALA1148279 | cell-based format | Scientific Literature | ||
16. | ALA881256 | ADME | Therapeutic index was expressed as ratio of LD50 for KB cell line to IC50 against Plasmodium falciparum | 35 | ALA1148279 | cell-based format | Scientific Literature | ||
17. | ALA880254 | Binding | Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coli | Trypanosoma brucei | 81 | ALA1141094 | assay format | Scientific Literature | |
18. | ALA883185 | Functional | Ratio of ED50 against KB cell line to that of IC50 of TbVSP1 | 34 | ALA1141094 | cell-based format | Scientific Literature | ||
19. | ALA872247 | Functional | Dose to inhibit the growth of human KB carcinoma cell line | Homo sapiens | 34 | ALA1141094 | cell-based format | Scientific Literature | |
20. | ALA1217000 | Functional | Antimicrobial activity against Plasmodium falciparum | Plasmodium falciparum | 630 | ALA1212812 | organism-based format | Scientific Literature |