# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA676676 | Functional | In vitro growth inhibition against Entamoeba histolytica | Entamoeba histolytica | 102 | ALA1148279 | organism-based format | Scientific Literature | |
2. | ALA679573 | Binding | Inhibitory activity against Leishmania major Farnesyl diphosphate synthase; ND denotes not determined | Leishmania major | 5 | ALA1148279 | single protein format | Scientific Literature | |
3. | ALA700364 | Toxicity | Toxicity evaluated against human nasopharyngeal carcinoma KB cell line | Homo sapiens | 102 | ALA1148279 | cell-based format | Scientific Literature | |
4. | ALA851069 | ADME | Therapeutic index was expressed as ratio of LD50 for KB cell line to IC50 against Entamoeba histolytica | 47 | ALA1148279 | cell-based format | Scientific Literature | ||
5. | ALA881256 | ADME | Therapeutic index was expressed as ratio of LD50 for KB cell line to IC50 against Plasmodium falciparum | 35 | ALA1148279 | cell-based format | Scientific Literature | ||
6. | ALA880254 | Binding | Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coli | Trypanosoma brucei | 81 | ALA1141094 | assay format | Scientific Literature | |
7. | ALA883185 | Functional | Ratio of ED50 against KB cell line to that of IC50 of TbVSP1 | 34 | ALA1141094 | cell-based format | Scientific Literature | ||
8. | ALA872247 | Functional | Dose to inhibit the growth of human KB carcinoma cell line | Homo sapiens | 34 | ALA1141094 | cell-based format | Scientific Literature | |
9. | ALA910461 | Functional | Antibacterial activity against Escherichia coli W3110 | Escherichia coli | 117 | ALA1138862 | organism-based format | Scientific Literature | |
10. | ALA910462 | Functional | Antibacterial activity against Escherichia coli pTMV19 | Escherichia coli | 47 | ALA1138862 | organism-based format | Scientific Literature | |
11. | ALA910463 | Functional | Antibacterial activity against Escherichia coli pTMV19 in presence of mevalonate | Escherichia coli | 47 | ALA1138862 | organism-based format | Scientific Literature | |
12. | ALA1217000 | Functional | Antimicrobial activity against Plasmodium falciparum | Plasmodium falciparum | 630 | ALA1212812 | organism-based format | Scientific Literature | |
13. | ALA1217007 | Functional | Antimicrobial activity against Entamoeba histolytica | Entamoeba histolytica | 304 | ALA1212812 | organism-based format | Scientific Literature | |
14. | ALA769481 | Functional | In vitro growth inhibition against Plasmodium falciparum | Plasmodium falciparum | 102 | ALA1148279 | organism-based format | Scientific Literature | |
15. | ALA998577 | Binding | Inhibition of the ATP-mediated HIV1 reverse transcriptase D67N/K70R/T215F/K219Q mutant catalyzed 3'-azido, 3'-deoxythymidine excision from AZT-terminated DNA primers | Human immunodeficiency virus 1 | 35 | ALA1141713 | assay format | Scientific Literature | |
16. | ALA2444359 | ADME | Cytotoxicity against human HepG2 cells assessed as cell viability at 100 uM after 48 hrs by MTT assay | Homo sapiens | 23 | ALA2439950 | cell-based format | Scientific Literature | |
17. | ALA2444629 | Functional | Cytotoxicity against mouse J774A1 cells assessed as cell viability at 100 uM after 48 hrs by MTT assay | Mus musculus | 23 | ALA2439950 | cell-based format | Scientific Literature | |
18. | ALA2444630 | Binding | Binding affinity to bone mineral hydroxyapatite assessed as adsorbed level at 100 uM after 2 hrs by UV-spectrophotometric analysis | 23 | ALA2439950 | assay format | Scientific Literature | ||
19. | ALA2444631 | Binding | Inhibition of MMP14 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay | Homo sapiens | 24 | ALA2439950 | single protein format | Scientific Literature | |
20. | ALA2444632 | Binding | Inhibition of MMP9 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay | Homo sapiens | 24 | ALA2439950 | single protein format | Scientific Literature |