# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA676676 | Functional | In vitro growth inhibition against Entamoeba histolytica | Entamoeba histolytica | 102 | ALA1148279 | organism-based format | Scientific Literature | |
2. | ALA679572 | Binding | Inhibitory activity against Leishmania major Farnesyl diphosphate synthase | Leishmania major | 43 | ALA1148279 | single protein format | Scientific Literature | |
3. | ALA689504 | Functional | Percent decrease of amebic liver abscess (mg) formation in Entamoeba histolytica infected hamsters (treated at 10 mg/kg ip once a day for 5 days) | Cricetulus griseus | 5 | ALA1148279 | organism-based format | Scientific Literature | |
4. | ALA689505 | Functional | Percent decrease of normal liver weight (mg) in Entamoeba histolytica infected hamsters (treated at 10 mg/kg ip once a day for 5 days) | Cricetulus griseus | 5 | ALA1148279 | organism-based format | Scientific Literature | |
5. | ALA690768 | Functional | Mean effect on amebic liver abscess (mg) formation in Entamoeba histolytica infected hamsters (treated at 10 mg/kg ip once a day for 5 days) | Cricetulus griseus | 5 | ALA1148279 | organism-based format | Scientific Literature | |
6. | ALA690769 | Functional | Mean effect on normal liver weight (mg) in Entamoeba histolytica infected hamsters (treated at 10 mg/kg ip once a day for 5 days) | Cricetulus griseus | 5 | ALA1148279 | organism-based format | Scientific Literature | |
7. | ALA700364 | Toxicity | Toxicity evaluated against human nasopharyngeal carcinoma KB cell line | Homo sapiens | 102 | ALA1148279 | cell-based format | Scientific Literature | |
8. | ALA851069 | ADME | Therapeutic index was expressed as ratio of LD50 for KB cell line to IC50 against Entamoeba histolytica | 47 | ALA1148279 | cell-based format | Scientific Literature | ||
9. | ALA880254 | Binding | Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coli | Trypanosoma brucei | 81 | ALA1141094 | assay format | Scientific Literature | |
10. | ALA883185 | Functional | Ratio of ED50 against KB cell line to that of IC50 of TbVSP1 | 34 | ALA1141094 | cell-based format | Scientific Literature | ||
11. | ALA872247 | Functional | Dose to inhibit the growth of human KB carcinoma cell line | Homo sapiens | 34 | ALA1141094 | cell-based format | Scientific Literature | |
12. | ALA865780 | Binding | Inhibitory activity against Trypanosoma cruzi hexokinase | Trypanosoma cruzi | 42 | ALA1148603 | single protein format | Scientific Literature | |
13. | ALA863956 | Functional | Cytotoxicity in human nasopharyngeal carcinoma KB cell line | Homo sapiens | 32 | ALA1148603 | cell-based format | Scientific Literature | |
14. | ALA865754 | ADME | Therapeutic index TI=LD50(KB)/IC50(TcHK) | 32 | ALA1148603 | assay format | Scientific Literature | ||
15. | ALA865755 | Functional | Cytotoxicity to Dictyostelium discoideum | Dictyostelium discoideum | 32 | ALA1148603 | organism-based format | Scientific Literature | |
16. | ALA858875 | Binding | Inhibitory activity against FPPS in Leishmania major | Leishmania major | 12 | ALA1148603 | single protein format | Scientific Literature | |
17. | ALA858827 | Functional | Growth inhibition of Trypanosoma cruzi intracellular amastigotes | Trypanosoma cruzi | 2 | ALA1148603 | organism-based format | Scientific Literature | |
18. | ALA910461 | Functional | Antibacterial activity against Escherichia coli W3110 | Escherichia coli | 117 | ALA1138862 | organism-based format | Scientific Literature | |
19. | ALA910462 | Functional | Antibacterial activity against Escherichia coli pTMV19 | Escherichia coli | 47 | ALA1138862 | organism-based format | Scientific Literature | |
20. | ALA910463 | Functional | Antibacterial activity against Escherichia coli pTMV19 in presence of mevalonate | Escherichia coli | 47 | ALA1138862 | organism-based format | Scientific Literature |