# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3584508 | Functional | Agonist activity at human recombinant mu opioid receptor expressed in CHO cells co-expressing C-terminally modified Galphaqi5 assessed as stimulation of calcium release up to 1 uM by Fluo-4 AM dye-based fluorescence assay | Homo sapiens | 3 | ALA3580572 | cell-based format | Scientific Literature | |
2. | ALA3584510 | Functional | Agonist activity at human recombinant delta opioid receptor expressed in CHO cells co-expressing Galphaq66Di5 assessed as stimulation of calcium release by Fluo-4 AM dye-based fluorescence assay | Homo sapiens | 9 | ALA3580572 | cell-based format | Scientific Literature | |
3. | ALA3584514 | Functional | Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells co-expressing C-terminally modified Galphaqi5 assessed as stimulation of calcium release up to 1 uM by Fluo-4 AM dye-based fluorescence assay | Homo sapiens | 2 | ALA3580572 | cell-based format | Scientific Literature | |
4. | ALA3635476 | Functional | Antitrichomonal activity against Trichomonas vaginalis after 48 hrs by invert microscope analysis | Trichomonas vaginalis | 9 | ALA3632589 | organism-based format | Scientific Literature | |
5. | ALA630098 | Physicochemical | Partition coefficient (logP) | 28 | ALA1136781 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA660030 | Binding | Binding affinity towards Cholecystokinin type B receptor was determined in guinea pig cortex using [3H]SNF8702 as radioligand | Cavia porcellus | 6 | ALA1129440 | tissue-based format | Scientific Literature | |
7. | ALA661826 | Binding | Binding affinity towards Cholecystokinin type A receptor was determined in guinea pig pancreatic membranes using [125I]-BH-CCK-8 as radioligand | Cavia porcellus | 6 | ALA1129440 | cell membrane format | Scientific Literature | |
8. | ALA664809 | ADME | Inhibition of human cytochrome P450 3A4 | 28 | ALA1136781 | single protein format | Scientific Literature | ||
9. | ALA666300 | Functional | Agonistic activity towards Opioid receptor delta 1 as inhibitory activity towards electrically stimulated mouse vas deferens | Mus musculus | 9 | ALA1129071 | tissue-based format | Scientific Literature | |
10. | ALA684413 | Functional | Effective concentration required for in vitro agonist potency in guinea-pig ileum myenteric plexus preparation (GPI) | Cavia porcellus | 3 | ALA1128801 | organism-based format | Scientific Literature | |
11. | ALA686707 | Functional | Percent maximal inhibition (Emax) was measured using guinea pig ileum assay (GPI). | Cavia porcellus | 7 | ALA1125258 | organism-based format | Scientific Literature | |
12. | ALA681784 | Functional | Inhibitory potency evaluated against electrically evoked contractions of guinea pig ileum | Cavia porcellus | 11 | ALA1124249 | organism-based format | Scientific Literature | |
13. | ALA681786 | Functional | Inhibitory potency was evaluated using strips of guinea pig ileum (GPI) longitudinal muscle-myenteric plexus. | Cavia porcellus | 5 | ALA1124942 | organism-based format | Scientific Literature | |
14. | ALA688347 | Functional | Ratio between IC50(GPI)/IC50(MVD) | Cavia porcellus | 5 | ALA1124942 | organism-based format | Scientific Literature | |
15. | ALA687391 | Functional | Concentration that reduced the response by 50% by delta receptor selective analogue was assessed in Guinea pig ileum assay | Cavia porcellus | 2 | ALA1124423 | organism-based format | Scientific Literature | |
16. | ALA844218 | Binding | Tested for binding affinity against mu opioid receptor fby displacing [3H]- DAMGO radioligand from rat brain membrane preparations | 6 | ALA1126861 | assay format | Scientific Literature | ||
17. | ALA843456 | Binding | Relative potency to that of [Leu5]- enkephalin | 6 | ALA1126861 | single protein format | Scientific Literature | ||
18. | ALA844029 | Functional | Ability to inhibit electrically evoked contractions of isolated muscle preparations of mouse vas deference (MVD, delta receptor) | 4 | ALA1135552 | assay format | Scientific Literature | ||
19. | ALA844030 | Functional | Ability to inhibit electrically evoked contractions of isolated muscle preparations of guinea pig ileum (GPI, mu receptor) | Cavia porcellus | 4 | ALA1135552 | tissue-based format | Scientific Literature | |
20. | ALA849220 | Binding | Binding affinity (Ki) ratio of mu to delta receptor | 6 | ALA1135552 | protein format | Scientific Literature |