# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA622149 | P | The compound was evaluated for the partition coefficient | 9 | ALA1126412 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA641221 | F | Acyl coenzyme A:cholesterol acyltransferase activity was determined in J774 macrophages by measuring the formation of labeled cholesteryl oleate (pmol/midmg) from [14C]oleoyl-CoA | 2 | ALA1128278 | assay format | Scientific Literature | ||
3. | ALA641222 | B | Acyl coenzyme A:cholesterol acyltransferase inhibition in cell culture measured in murine IC-21 macrophages. | 51 | ALA1128278 | assay format | Scientific Literature | ||
4. | ALA641890 | B | Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay. | Mus musculus | 37 | ALA1128038 | cell-based format | Scientific Literature | |
5. | ALA642358 | B | Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture | Mus musculus | 33 | ALA1128040 | cell-based format | Scientific Literature | |
6. | ALA638624 | B | In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomes | Rattus norvegicus | 17 | ALA1128039 | microsome format | Scientific Literature | |
7. | ALA646057 | B | In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomes by using AIV assay. | Rattus norvegicus | 38 | ALA1128038 | microsome format | Scientific Literature | |
8. | ALA646706 | B | In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assay | Rattus norvegicus | 20 | ALA1128040 | microsome format | Scientific Literature | |
9. | ALA645923 | B | Compound was evaluated for the Acyl coenzyme A:cholesterol acyltransferase inhibition using microsomes isolated from the livers of cholesterol fed rats. | Rattus norvegicus | 1 | ALA1127335 | tissue-based format | Scientific Literature | |
10. | ALA645926 | B | In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes | Rattus norvegicus | 53 | ALA1127371 | microsome format | Scientific Literature | |
11. | ALA641702 | B | Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome. | Rattus norvegicus | 50 | ALA1128278 | microsome format | Scientific Literature | |
12. | ALA660742 | B | Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liver; No data | Oryctolagus cuniculus | 1 | ALA1126412 | assay format | Scientific Literature | |
13. | ALA660744 | B | Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liver | Rattus norvegicus | 9 | ALA1126412 | assay format | Scientific Literature | |
14. | ALA687086 | F | Evaluated for Syrian hamsters fed with 0.8% cholesterol-supplemented chow diet for 7 days | Cricetulus griseus | 1 | ALA1127371 | organism-based format | Scientific Literature | |
15. | ALA687087 | F | Evaluated for Syrian hamsters fed with 2.5% cholesterol-supplemented chow diet for 3 days | Cricetulus griseus | 1 | ALA1127371 | organism-based format | Scientific Literature | |
16. | ALA686920 | F | Tested anti-hypercholesterolaemic value(AHV) is the ratio of observed reduction in serum cholesterol to difference between control and baseline levels x100 at 10 mg/kg/day dose | Cricetulus griseus | 7 | ALA1127371 | organism-based format | Scientific Literature | |
17. | ALA690249 | F | In vivo activity, with an ED50 inlowering cholesterol levels in the cholesterol-fed hamster | Cricetulus griseus | 1 | ALA1128039 | organism-based format | Scientific Literature | |
18. | ALA697014 | F | Tested for effective dose required to lower the serum cholesterol levels in hamsters | Cricetulus griseus | 1 | ALA1128040 | organism-based format | Scientific Literature | |
19. | ALA699376 | F | Concentration required to inhibit 50% activity of J774 macrophage cholesterol esterification | Mus musculus | 2 | ALA1128278 | cell-based format | Scientific Literature | |
20. | ALA767533 | F | Hypercholesterolemic activity in rats at a dose of 1 mg/kg of compound was determined | Rattus norvegicus | 2 | ALA1127335 | organism-based format | Scientific Literature |