# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA660002 | B | Binding affinity was determined by displacement of [3H]P1075 from its binding sites in canine cardiac membranes | Canis lupus familiaris | 15 | ALA1131338 | cell membrane format | Scientific Literature | |
2. | ALA682585 | F | Compound was evaluated for its hypotensive activity (decrease in blood pressure) in male guinea pigs. | Cavia porcellus | 5 | ALA1149931 | organism-based format | Scientific Literature | |
3. | ALA682586 | F | Compound was evaluated in vivo for its ability to inhibit methacholine induced bronchospasm in male guinea pig. | Cavia porcellus | 3 | ALA1149931 | organism-based format | Scientific Literature | |
4. | ALA684405 | F | The compound was tested for hypotensive activity against guinea pig detrusor (bladder) strip mildly depolarized with 15 mM KCl | Cavia porcellus | 5 | ALA1127163 | organism-based format | Scientific Literature | |
5. | ALA684406 | F | The compound was tested for hypotensive activity against guinea pig detrusor (bladder) strip mildly depolarized with 15 mM KCl | Cavia porcellus | 10 | ALA1127164 | organism-based format | Scientific Literature | |
6. | ALA686711 | F | The compound was tested for hypotensive activity against guinea pig detrusor (bladder) strip mildly depolarized with 15 mM KCl | Cavia porcellus | 7 | ALA1150458 | organism-based format | Scientific Literature | |
7. | ALA686712 | F | The compound was tested for hypotensive activity against guinea pig vascular tissue (portal vein) strip mildly depolarized with 15 mM KCl | Cavia porcellus | 2 | ALA1127163 | organism-based format | Scientific Literature | |
8. | ALA686713 | F | The compound was tested for hypotensive activity against guinea pig vascular tissue (portal vein) strip mildly depolarized with 15 mM KCl | Cavia porcellus | 3 | ALA1127164 | organism-based format | Scientific Literature | |
9. | ALA686714 | F | The compound was tested for hypotensive activity against guinea pig vascular tissue (portal vein) strip mildly depolarized with 15 mM KCl | Cavia porcellus | 2 | ALA1150458 | organism-based format | Scientific Literature | |
10. | ALA684968 | F | Tested for relaxation of guinea pig trachealis smooth muscle | Cavia porcellus | 8 | ALA1152008 | organism-based format | Scientific Literature | |
11. | ALA686670 | F | Concentration required to inhibit spontaneous tone of guinea pig isolated tracheal spirals | Cavia porcellus | 10 | ALA1149931 | organism-based format | Scientific Literature | |
12. | ALA686671 | F | Inhibition of spontaneous tone of guinea pig isolated tracheal spirals in the presence of glibenclamide (1 uM) | Cavia porcellus | 2 | ALA1149931 | tissue-based format | Scientific Literature | |
13. | ALA696078 | F | Tested for the ability to inhibit spontaneous tone in guinea pig trachealis by 50%, activity expresses as negative logarithm of molar concentration | Cavia porcellus | 9 | ALA1152008 | organism-based format | Scientific Literature | |
14. | ALA701213 | F | Evaluated for K-ATP activity in terms of change in membrane potential through guinea pig bladder assay | Cavia porcellus | 68 | ALA1148324 | cell membrane format | Scientific Literature | |
15. | ALA701214 | F | Evaluated for K-ATP activity in terms of membrane potential change, through guinea pig bladder assay | Cavia porcellus | 51 | ALA1148325 | cell membrane format | Scientific Literature | |
16. | ALA701216 | F | Evaluated for K-ATP activity in terms of stable twitch response through field-stimulated landrace pig detrusor assay | Sus scrofa | 36 | ALA1148324 | assay format | Scientific Literature | |
17. | ALA878707 | F | K-ATP activity in terms of stable twitch response through field-stimulated landrace pig detrusor assay | Sus scrofa | 26 | ALA1148325 | assay format | Scientific Literature | |
18. | ALA699663 | F | Evaluated for K-ATP activity as in vitro bladder relaxation in spontaneous Landrace pig detrusor strips (SLPD) | Sus scrofa | 6 | ALA1148324 | assay format | Scientific Literature | |
19. | ALA759787 | F | Evaluated for change in heart rate from baseline at a plasma concentration of 12 nM in pigs | Sus scrofa | 1 | ALA1148324 | organism-based format | Scientific Literature | |
20. | ALA759788 | F | Evaluated for change in heart rate from baseline at a plasma concentration of 167 nM in pigs | Sus scrofa | 1 | ALA1148324 | organism-based format | Scientific Literature |