| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1794345 | F | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 170,142 | organism-based format | PubChem BioAssays | ||
| 2. | ALA1794580 | F | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 130,890 | organism-based format | PubChem BioAssays | ||
| 3. | ALA1614161 | F | PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] | Schistosoma mansoni | 28,392 | assay format | PubChem BioAssays | ||
| 4. | ALA1614087 | F | PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) | Mus musculus | 51,950 | assay format | PubChem BioAssays | ||
| 5. | ALA4413386 | B | Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates assessed as residual activity at 100 uM using DAG as substrate measured after 5 mins in presence of [gamma-32P]ATP by TLC analysis relative to control | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 6. | ALA4413387 | B | Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [gamma-32P]ATP by TLC analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4413388 | B | Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates at 100 uM using DAG as substrate measured after 5 mins in presence of [gamma-32P]ATP by TLC analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4413389 | B | Inhibition of DGKzeta (unknown origin) expressed in human 293T cells at 100 uM using DAG as substrate measured after 5 mins in presence of [gamma-32P]ATP by TLC analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4413390 | B | Inhibition of DGKdelta (unknown origin) expressed in human 293T cells at 100 uM using DAG as substrate measured after 5 mins in presence of [gamma-32P]ATP by TLC analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4413391 | A | Antagonist activity at serotonin receptor in human PBMC assessed as inhibition of PMA-stimulated superoxide anion generation at 10 uM preincubated for 1 hr followed by PMA-stimulation and measured after 30 mins by spectrophotometric method | Homo sapiens | 4 | protein format | Scientific Literature | ||
| 11. | ALA4413392 | A | Cytotoxicity against human Jurkat cells assessed as reduction in cell viability at 1 uM after 24 hrs by trypan blue exclusion assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA4413393 | B | Inhibition of DGKalpha in OKT3-induced human Jurkat cells harboring SAP ShRNA assessed as restoration of restimulation-induced cell death at 1 uM measured after 24 hrs by trypan blue exclusion method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA4413394 | B | Inhibition of DGKalpha in PHA-induced human Jurkat cells harboring SAP ShRNA assessed as restoration of restimulation-induced cell death at 1 uM measured after 24 hrs by trypan blue exclusion method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA4413395 | B | Effect on TCR signaling in OKT3-induced human T-cells harboring SiRNA assessed as restoration of restimulation-induced cell death at 1 to 10 uM preincubated for 30 mins followed by OKT3 stimulation and measured 24 hrs post dose by propidium iodide staining based flow cytometry | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 15. | ALA4413396 | A | Cytotoxicity against human T cells assessed as cell death at 1 to 10 uM measured after 24 hrs propidium iodide staining based flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4413397 | B | Inhibition of DGKalpha in OKT3-induced human T cells harboring SAP SiRNA assessed as restoration of restimulation-induced cell death at 1 to 10 uM preincubated for 30 mins followed by OKT3 stimulation and measured 24 hrs post dose by propidium iodide staining based flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4413400 | B | Inhibition of DGKalpha in OKT3-induced human T cells harboring SAP siRNA assessed as restoration of TCR-induced NR4A1 upregulation at 10 uM after 4 hrs by RT-PCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4413401 | B | Inhibition of DGKalpha in OKT3-induced human T cells harboring SAP siRNA assessed as restoration of TCR-induced NR4A3 upregulation at 10 uM after 4 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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